Date published: 2025-12-25

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copGFP Inhibitors

COP-GFP inhibitors constitute a diverse and intricate chemical class characterized by their capacity to impede the function or activity of the COP-GFP fusion protein. COP-GFP, also known as Coat Protein I-Green Fluorescent Protein, is widely utilized as a fluorescent marker in cellular investigations to elucidate intracellular trafficking and transport dynamics. These inhibitors are meticulously developed to intricately disrupt the mechanisms associated with COP-GFP-mediated processes, enabling researchers to unravel the complexities of vesicle transport within cells. This chemical class encompasses a broad range of compounds, each engineered to target specific components or pathways intricately linked to COP-GFP function. From those that inhibit Arf1, a protein essential for vesicle formation, to those that modulate Golgi-associated proteins like GBF1, these inhibitors serve as critical tools for discerning the underlying intricacies of intracellular transport pathways.

By precisely interfacing with the molecular machinery associated with COP-GFP, these chemical entities hold the potential to advance our understanding of cellular dynamics and contribute to the broader comprehension of cellular processes involving vesicle trafficking. The development and refinement of COP-GFP inhibitors underscore the meticulous scientific endeavor aimed at dissecting the subtleties of intracellular transport, providing researchers with invaluable insights into the molecular orchestration of cellular architecture.

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$30.00
$52.00
$122.00
$367.00
25
(3)

Brefeldin A is a well-known inhibitor that disrupts COP-GFP function by interfering with vesicle formation and trafficking between the endoplasmic reticulum (ER) and Golgi apparatus.

Golgicide A

1005036-73-6sc-215103
sc-215103A
5 mg
25 mg
$187.00
$670.00
11
(1)

Golgicide A specifically inhibits the activity of the Golgi-associated protein Arf1, which is essential for COP-GFP-mediated vesicle transport.

Exo2

304684-77-3sc-215011
sc-215011A
5 mg
25 mg
$87.00
$282.00
1
(0)

Exo2 is a synthetic small molecule inhibitor that targets the Sec7 domain of Arf-GEF (Guanine nucleotide exchange factor), blocking COP-GFP function.