Date published: 2026-4-11

1-800-457-3801

SCBT Portrait Logo
Seach Input

connexin (GJA; gap junction) Inhibitors

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-APB

524-95-8sc-201487
sc-201487A
20 mg
100 mg
$28.00
$53.00
37
(1)

Influences intracellular calcium levels, which can indirectly modulate connexin function.

Mefenamic acid

61-68-7sc-205380
sc-205380A
25 g
100 g
$106.00
$208.00
6
(0)

Similar to flufenamic acid, can disrupt gap junction communication.

Quinidine

56-54-2sc-212614
10 g
$104.00
3
(1)

Stereoisomer of quinine, which also inhibits gap junction communication.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Protein kinase C activator that can modulate connexin-based gap junction communication.

Carbenoxolone disodium

7421-40-1sc-203868
sc-203868A
sc-203868B
sc-203868C
1 g
5 g
10 g
25 g
$46.00
$201.00
$358.00
$774.00
1
(3)

Carbenoxolone is a glycyrrhetinic acid derivative that inhibits connexin 43 by blocking gap junction intercellular communication. It binds to the connexin proteins and interferes with channel pore formation. Non-specific gap junction blocker. Can inhibit gap junction intercellular communication mediated by connexins.

Meclofenamic Acid

644-62-2sc-211780
5 mg
$402.00
(0)

Meclofenamic acid is a compound that inhibits connexin hemichannels. It does this by blocking the channel pore, preventing the exchange of ions and small molecules.

Lanthanum(III) chloride

10099-58-8sc-257661
10 g
$90.00
(0)

Lanthanum Chloride is a gap junction blocker that inhibits connexin by interacting with the channel pore. It prevents the exchange of ions and other small molecules, disrupting gap junction communication.