CHSY3 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, has been shown to reduce chondroitin sulfate synthesis in certain cell types. By inhibiting certain kinases, genistein can affect the pathways leading up to CHSY3's activity in CS synthesis. | ||||||
Swainsonine | 72741-87-8 | sc-201362 sc-201362C sc-201362A sc-201362D sc-201362B | 1 mg 2 mg 5 mg 10 mg 25 mg | $138.00 $251.00 $631.00 $815.00 $1832.00 | 6 | |
Swainsonine inhibits mannose 6-phosphate isomerase, affecting oligosaccharide synthesis. As oligosaccharides serve as substrates for chondroitin sulfate synthesis, this can indirectly modulate CHSY3 activity. | ||||||
4-Methylumbelliferyl-β-D-xylopyranoside | 6734-33-4 | sc-220964 sc-220964A | 25 mg 100 mg | $71.00 $233.00 | ||
Another xyloside analog that can act as an alternative primer for CS chain initiation, potentially leading to altered CS synthesis and indirectly modulating CHSY3. | ||||||
4-Nitrophenyl-β-D- xylopyranoside | 2001-96-9 | sc-281430 sc-281430A | 500 mg 1 g | $268.00 $493.00 | ||
This compound is a known inhibitor of beta4GalT7, an enzyme involved in the initiation of CS chain synthesis. Inhibition of this upstream enzyme can indirectly reduce CHSY3's substrate availability. | ||||||
Rhodamine B | 81-88-9 | sc-203756 sc-203756A sc-203756B | 25 g 100 g 500 g | $37.00 $73.00 $226.00 | 6 | |
It has been found to reduce glycosaminoglycan synthesis, including chondroitin sulfate, in some settings. Inhibiting the synthesis process can indirectly impact CHSY3 activity. | ||||||
Sodium chlorate | 7775-09-9 | sc-212938 | 100 g | $59.00 | 1 | |
Chlorate can inhibit sulfation processes, which are necessary for chondroitin sulfate's structure. Disrupting sulfation indirectly affects CS synthesis and CHSY3's role therein. | ||||||