CHST7 Activators
Compounds like PAPS, Sodium sulfate, and ATP are directly involved in the synthesis and availability of the sulfonate donor required for CHST7's sulfotransferase activity. PAPS is the primary sulfonate donor in sulfation reactions, and its availability is crucial for CHST7 functionality. Sodium sulfate acts as a sulfate source, while ATP is required for PAPS synthesis. Enhancing the levels of these compounds can lead to increased CHST7 activity by ensuring an adequate supply of necessary substrates.
Additionally, cofactors and substrates such as Magnesium chloride, Manganese(II) sulfate, and Nitrophenyl sulfate play significant roles in optimizing the catalytic efficiency and substrate availability for CHST7. Magnesium and manganese ions serve as essential cofactors for sulfotransferases, including CHST7, ensuring optimal enzyme function. Natural substrates and molecules undergoing sulfation in biological processes, such as Estradiol, Dopamine, and Chondroitin sulfate, provide a diverse range of targets for CHST7, enhancing its activity by increasing the demand for sulfation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium sulfate anhydrous | 7757-82-6 | sc-212945 sc-212945A | 500 g 1 kg | $62.00 $89.00 | ||
Sodium sulfate can be used as a source of sulfate in cells. Its availability is crucial for the generation of PAPS, potentially enhancing CHST7 activity. | ||||||
Heparin | 9005-49-6 | sc-507344 | 25 mg | $117.00 | 1 | |
Heparin, a highly sulfated glycosaminoglycan, may influence CHST7 indirectly by modulating the cellular environment and demand for sulfated compounds. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Magnesium ions are essential cofactors for many enzymes, including sulfotransferases. Magnesium chloride can enhance CHST7 activity by optimizing enzyme function. | ||||||
Manganese(II) sulfate monohydrate | 10034-96-5 | sc-203130 sc-203130A | 100 g 500 g | $40.00 $105.00 | ||
Manganese ions can act as cofactors for sulfotransferases. Manganese(II) sulfate may enhance CHST7 activity by improving its catalytic efficiency. | ||||||
Potassium p-Nitrophenyl Sulphate | 6217-68-1 | sc-219633 sc-219633A sc-219633B | 500 mg 1 g 5 g | $75.00 $105.00 $360.00 | ||
Nitrophenyl sulfate can serve as a sulfotransferase substrate. Its presence can help in assessing and potentially enhancing CHST7 activity. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estradiol undergoes sulfation, a reaction catalyzed by sulfotransferases. Its presence might enhance CHST7 activity indirectly by increasing substrate demand. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine can be sulfated by certain sulfotransferases. The presence of dopamine may increase CHST7 activity by increasing the range of substrates. | ||||||
Chondroitin Sulfate, Bovine | 9007-28-7 | sc-203888 | 5 g | $92.00 | 1 | |
As a natural substrate for sulfotransferases, chondroitin sulfate's presence might enhance CHST7 activity by increasing demand for sulfation. | ||||||