CHRNB4 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytisine | 485-35-8 | sc-203015 sc-203015A | 5 mg 25 mg | $56.00 $190.00 | ||
Cytisine acts as a potent agonist at nicotinic acetylcholine receptors, exhibiting a unique ability to mimic acetylcholine. Its structural features facilitate strong interactions with receptor subtypes, leading to distinct signaling cascades. The compound's rapid kinetics enable swift receptor activation, influencing neurotransmitter release. Additionally, its hydrophilic nature enhances solubility, affecting distribution and interaction with biological membranes, ultimately shaping its pharmacodynamic profile. | ||||||
Pyrantel Pamoate | 22204-24-6 | sc-205823 sc-205823A | 5 g 10 g | $84.00 $136.00 | ||
Pyrantel Pamoate exhibits unique properties as a selective neuromuscular blocking agent, primarily through its action on nicotinic receptors in invertebrates. Its distinct molecular structure allows for effective binding, disrupting synaptic transmission. The compound's lipophilic characteristics enhance membrane permeability, facilitating rapid uptake. Furthermore, its dual salt form contributes to stability and solubility, influencing its reactivity and interaction with biological systems, thereby shaping its overall behavior. | ||||||
(S)-Anabasine | 494-52-0 | sc-212875 | 100 mg | $683.00 | ||
(S)-Anabasine is characterized by its chiral nature, which influences its interaction with nicotinic acetylcholine receptors, leading to selective modulation of neurotransmission. Its unique stereochemistry allows for specific binding affinities, impacting synaptic efficacy. The compound's hydrophobic regions enhance its ability to traverse lipid membranes, while its dynamic conformational flexibility may affect reaction kinetics and molecular interactions, contributing to its distinct biological behavior. | ||||||
Galanthamine | 357-70-0 | sc-218556 | 10 mg | $320.00 | ||
Galanthamine allosterically potentiates CHRNB4 receptor activity by binding to a modulatory site, enhancing acetylcholine's effect. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $122.00 $281.00 $388.00 $683.00 $1428.00 $3060.00 | 12 | |
Carbachol mimics acetylcholine action at CHRNB4 receptors, inducing activation and increased ion permeability. | ||||||
PNU-282,987 | 123464-89-1 | sc-200187 sc-200187A | 10 mg 50 mg | $170.00 $576.00 | 3 | |
PNU-282987 is a selective agonist for the alpha7 subtype of nicotinic acetylcholine receptors that also compose CHRNB4, leading to receptor activation. | ||||||
Sazetidine A dihydrochloride | 820231-95-6 | sc-203256 | 1 mg | $186.00 | ||
Sazetidine-A acts as a selective partial agonist at CHRNB4 subunit-containing receptors, increasing their activity. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol Hydrochloride is a non-selective beta-adrenergic agonist that can facilitate the release of acetylcholine, indirectly enhancing CHRNB4 receptor activity. | ||||||
(±)-Coniine | 3238-60-6 | sc-252626B sc-252626 sc-252626A | 500 mg 1 g 5 g | $204.00 $316.00 $867.00 | ||
Coniine binds to nicotinic acetylcholine receptors including those with CHRNB4, causing stimulation and increased neurotransmission. | ||||||