CD26 Inhibitors
Items 21 to 26 of 26 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Omarigliptin | 1226781-44-7 | sc-507282 | 5 mg | $337.00 | ||
Omarigliptin is a long-acting DPP-4 inhibitor that provides sustained inhibition of CD2It is used to improve blood sugar levels in adults with type 2 diabetes. | ||||||
(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine | 767340-03-4 | sc-206586 | 5 mg | $330.00 | ||
The compound (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine exhibits notable interactions with CD26, characterized by its ability to form stable π-π stacking and electrostatic interactions. These interactions modulate the enzyme's conformational landscape, influencing its catalytic efficiency. The trifluoromethyl and trifluorophenyl groups enhance electron-withdrawing properties, impacting reactivity and selectivity in enzymatic processes. | ||||||
Evogliptin | 1222102-29-5 | sc-507284 | 5 mg | $1060.00 | ||
Evogliptin is a DPP-4 inhibitor that acts by prolonging the activity of incretin hormones. | ||||||
Trelagliptin | 865759-25-7 | sc-507285 | 5 mg | $405.00 | ||
Trelagliptin is a CD26 inhibitor which helps to increase the levels of GLP-1 and GIP, leading to improved glucose regulation. | ||||||
Saroglitazar | 495399-09-2 | sc-473154 | 2.5 mg | $430.00 | ||
Saroglitazar is a dual PPAR (peroxisome proliferator-activated receptor) agonist and CD26 inhibitor. It is used for dyslipidemia and may also have potential benefits in managing type 2 diabetes. | ||||||
Sitagliptin | 486460-32-6 | sc-482298 sc-482298A sc-482298B | 25 mg 100 mg 1 g | $213.00 $473.00 $733.00 | 10 | |
Sitagliptin, as a CD26 modulator, engages in unique hydrogen bonding and hydrophobic interactions that significantly alter the enzyme's active site dynamics. Its structural features promote specific conformational changes, enhancing substrate affinity and influencing reaction kinetics. The presence of electron-withdrawing groups contributes to its reactivity profile, allowing for selective interactions that can fine-tune enzymatic pathways and affect downstream signaling mechanisms. | ||||||