Molecular structure of Omarigliptin, CAS Number: 1226781-44-7
Omarigliptin (CAS 1226781-44-7)
Alternate Names:
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine; MK-3102
CAS Number:
1226781-44-7
Molecular Weight:
398.4
Molecular Formula:
C17H20F2N4O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Omarigliptin (CAS 1226781-44-7) References
- Omarigliptin decreases inflammation and insulin resistance in a pleiotropic manner in patients with type 2 diabetes. | Hattori, S. 2020. Diabetol Metab Syndr. 12: 24. PMID: 32211075
- Omarigliptin Mitigates Lipopolysaccharide-Induced Neuroinflammation and Dysfunction of the Integrity of the Blood-Brain Barrier. | Du, H. and Wang, S. 2020. ACS Chem Neurosci. 11: 4262-4269. PMID: 33237730
- Omarigliptin protects against nonalcoholic fatty liver disease by ameliorating oxidative stress and inflammation. | Li, Z., et al. 2021. J Biochem Mol Toxicol. 35: e22914. PMID: 34533252
- The effects of Omarigliptin on promoting osteoblastic differentiation. | Liao, F., et al. 2021. Bioengineered. 12: 11837-11846. PMID: 34787070
- Efficacy of omarigliptin, once-weekly dipeptidyl peptidase-4 inhibitor, in patients with type 2 diabetes. | Kawasaki, E., et al. 2021. World J Diabetes. 12: 2087-2095. PMID: 35047122
- Omarigliptin/galangin combination mitigates lipopolysaccharide-induced neuroinflammation in rats: Involvement of glucagon-like peptide-1, toll-like receptor-4, apoptosis and Akt/GSK-3β signaling. | Kabel, AM., et al. 2022. Life Sci. 295: 120396. PMID: 35157909
- Omarigliptin alleviates cognitive dysfunction in Streptozotocin-induced diabetic mouse. | Li, X., et al. 2022. Bioengineered. 13: 9387-9396. PMID: 35389830
- Omarigliptin attenuates rotenone-induced Parkinson's disease in rats: Possible role of oxidative stress, endoplasmic reticulum stress and immune modulation. | Michel, HE., et al. 2022. Food Chem Toxicol. 164: 113015. PMID: 35439590
- Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice. | Zhang, Y., et al. 2023. J Inflamm Res. 16: 2535-2548. PMID: 37342770
- Omarigliptin inhibits brain cell ferroptosis after intracerebral hemorrhage. | Zhang, Y., et al. 2023. Sci Rep. 13: 14339. PMID: 37658227
Inhibitor of:
CD26, DPP10, and DPPA4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Omarigliptin, 5 mg | sc-507282 | 5 mg | $337.00 |