CD26 Inhibitors
Items 11 to 20 of 26 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dipeptidylpeptidase IV Inhibitor III | 866396-34-1 | sc-202582 | 5 mg | $450.00 | ||
Dipeptidylpeptidase IV Inhibitor III exhibits a remarkable capacity to modulate CD26 activity via its unique structural features, which facilitate selective binding to the enzyme's active site. The compound's conformational flexibility allows it to adopt various orientations, enhancing its interaction with substrate molecules. Its reactivity profile as an acid halide enables it to engage in specific molecular interactions, influencing enzymatic pathways and altering kinetic parameters in biochemical processes. | ||||||
8-(Bromomethyl)isoquinoline | 942579-56-8 | sc-394426 | 250 mg | $380.00 | ||
8-(Bromomethyl)isoquinoline demonstrates intriguing interactions with CD26, characterized by its ability to form stable complexes through non-covalent interactions. The compound's unique isoquinoline scaffold allows for π-π stacking and hydrogen bonding, which can influence the enzyme's conformation. Its reactivity as an electrophilic species facilitates selective modifications of amino acid residues, potentially altering enzymatic dynamics and impacting downstream signaling pathways. | ||||||
Anagliptin | 739366-20-2 | sc-507278 | 5 mg | $280.00 | ||
Anagliptin is a CD26 inhibitor that helps to increase GLP-1 and GIP levels, which can aid in controlling blood sugar. | ||||||
PK 44 phosphate | 1017682-66-4 | sc-361294 | 10 mg | $322.00 | ||
PK 44 phosphate exhibits distinctive interactions with CD26, primarily through its phosphate group, which enhances electrostatic interactions with the enzyme's active site. This compound can induce conformational changes in CD26, promoting altered substrate specificity. Its behavior as an acid halide allows for rapid acylation reactions, influencing the kinetics of protein modifications. Additionally, the presence of halogen atoms can enhance reactivity, leading to unique pathways in cellular signaling. | ||||||
Teneligliptin | 760937-92-6 (free base) | sc-475074 | 25 mg | $260.00 | 1 | |
Teneligliptin is a relatively newer CD26 inhibitor that has been approved for use in some countries to manage type 2 diabetes. It works by inhibiting DPP-4, thus prolonging the effects of incretin hormones. | ||||||
Dipeptidylpeptidase IV Inhibitor II | 1258008-19-3 | sc-221547 | 1 mg | $149.00 | ||
Dipeptidylpeptidase IV Inhibitor II engages with CD26 through specific hydrogen bonding and hydrophobic interactions, stabilizing its conformation. This compound modulates enzyme activity by altering the dynamics of substrate binding, which can affect downstream signaling pathways. Its unique structure facilitates selective inhibition, impacting reaction rates and influencing the overall enzymatic landscape. The presence of functional groups enhances its reactivity, allowing for nuanced interactions within cellular environments. | ||||||
Vildagliptin | 274901-16-5 | sc-208485 | 10 mg | $176.00 | 4 | |
Vildagliptin acts as a selective inhibitor of the enzyme CD26, showcasing unique binding interactions that stabilize the enzyme-substrate complex. Its molecular structure facilitates specific conformational changes upon binding, influencing the enzyme's catalytic activity. The compound exhibits distinct reaction kinetics, characterized by a moderate affinity that allows for effective modulation of enzymatic pathways. Additionally, Vildagliptin's solubility properties enhance its interaction dynamics in biochemical environments. | ||||||
Berberine hemisulfate | 633-66-9 | sc-202496 | 1 g | $32.00 | 3 | |
Berberine hemisulfate exhibits a distinctive affinity for CD26, characterized by its ability to form intricate electrostatic interactions and pi-stacking with aromatic residues. This compound influences the enzyme's conformational flexibility, thereby modulating substrate accessibility and catalytic efficiency. Its unique molecular architecture promotes selective binding, which can lead to altered kinetic profiles and downstream effects on cellular signaling networks. The presence of sulfate groups further enhances its solubility and interaction potential in biological systems. | ||||||
Gemigliptin tartrate | 1374639-74-3 | sc-507281 | 10 mg | $165.00 | ||
Gemigliptin is another DPP-4 inhibitor that helps to enhance the activity of GLP-1 and GIP, promoting better glycemic control. | ||||||
Sitagliptin maleate adduct | sc-473993 | 10 mg | $380.00 | |||
Sitagliptin maleate adduct demonstrates a unique interaction with CD26 through specific hydrogen bonding and hydrophobic contacts, which stabilize its binding conformation. This compound influences the enzyme's activity by altering its structural dynamics, potentially affecting substrate turnover rates. The presence of functional groups enhances its solubility and facilitates diverse molecular interactions, contributing to its distinct reactivity and behavior in biochemical pathways. | ||||||