Molecular structure of Anagliptin, CAS Number: 739366-20-2
Anagliptin (CAS 739366-20-2)
Alternate Names:
N-[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]-2-methylpropyl]-2-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxamide
CAS Number:
739366-20-2
Molecular Weight:
383.5
Molecular Formula:
C19H25N7O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Anagliptin (CAS 739366-20-2) References
- Anagliptin inhibits neointimal hyperplasia after balloon injury via endothelial cell-specific modulation of SOD-1/RhoA/JNK signaling in the arterial wall. | Li, Q., et al. 2018. Free Radic Biol Med. 121: 105-116. PMID: 29715547
- Anagliptin ameliorates high glucose- induced endothelial dysfunction via suppression of NLRP3 inflammasome activation mediated by SIRT1. | Jiang, T., et al. 2019. Mol Immunol. 107: 54-60. PMID: 30660990
- Anagliptin protects neuronal cells against endogenous amyloid β (Aβ)-induced cytotoxicity and apoptosis. | Chen, Z., et al. 2019. Artif Cells Nanomed Biotechnol. 47: 2213-2220. PMID: 31159590
- Anagliptin stimulates osteoblastic cell differentiation and mineralization. | Dong, C., et al. 2020. Biomed Pharmacother. 129: 109796. PMID: 32559615
- Anagliptin Protected against Hypoxia/Reperfusion-Induced Brain Vascular Endothelial Permeability by Increasing ZO-1. | Li, C., et al. 2021. ACS Omega. 6: 7771-7777. PMID: 33778288
- Anagliptin prevented interleukin 1β (IL-1β)-induced cellular senescence in vascular smooth muscle cells through increasing the expression of sirtuin1 (SIRT1). | Zhao, J., et al. 2021. Bioengineered. 12: 3968-3977. PMID: 34288819
- Anagliptin alleviates lipopolysaccharide-induced inflammation, apoptosis and endothelial dysfunction of lung microvascular endothelial cells. | Zhang, J. and Liu, L. 2021. Exp Ther Med. 22: 1472. PMID: 34737812
- Anagliptin Monotherapy for Six Months in Patients With Type 2 Diabetes Mellitus and Hyper-Low-Density Lipoprotein Cholesterolemia Reduces Plasma Levels of Fasting Low-Density Lipoprotein Cholesterol and Lathosterol: A Single-Arm Intervention Trial. | Ikegami, Y., et al. 2021. J Clin Med Res. 13: 502-509. PMID: 34925661
- Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages. | Yu, F., et al. 2022. Int Immunopharmacol. 104: 108514. PMID: 35045357
- Anagliptin promotes apoptosis in mouse colon carcinoma cells via MCT-4/lactate-mediated intracellular acidosis. | Li, Q., et al. 2022. Exp Ther Med. 23: 282. PMID: 35317435
Inhibitor of:
CD26, DPP10, and DPPA4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Anagliptin, 5 mg | sc-507278 | 5 mg | $280.00 |