Date published: 2026-4-24

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CD223 Antibodies

Santa Cruz Biotechnology features a diverse variety of CD223 monoclonal antibodies for advanced research in immunology and cell biology. CD223 monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CD223, also known as LAG-3, is a critical immune checkpoint protein that plays a significant role in regulating T cell activation and maintaining immune homeostasis. By inhibiting the proliferation and function of T cells, CD223 is essential in preventing autoimmunity and modulating immune responses during infections and cancer. Understanding CD223 function is crucial for developing therapeutic strategies aimed at enhancing anti-tumor immunity and improving vaccine efficacy. CD223 research has revealed important insights into immune system regulation and potential therapeutic applications. Ongoing studies continue to uncover new aspects of CD223's role in immune responses and disease progression. Research utilizing CD223 monoclonal antibodies has led to significant breakthroughs in understanding immune checkpoint regulation. Santa Cruz Biotechnology monoclonal antibodies for CD223 support researchers worldwide in advancing our understanding of immune system regulation and developing new therapeutic approaches.

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CD223 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CD223 Antibody (D-8)

sc-514993mouse IgG2b κ375-396 (h)WB, IP, IF, ELISAm, r, h
1
(5)

CD223 Antibody (C9B7W)

sc-32750rat IgG1FL (m)FCMm
1
(1)

CD223 CRISPR Knockout, HDR and Double Nickase Plasmids

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CD223 CRISPR/Cas9 KO Plasmid (h)

sc-406616hGene KnockoutGFP0
(0)

CD223 HDR Plasmid (h)

sc-406616-HDRhHomology Directed RepairPuromycin0
(0)

CD223 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD223 CRISPR Activation Plasmid (h)

sc-406616-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD223 CRISPR Activation Plasmid (h2)

sc-406616-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CD223 Lentiviral Activation Particles (h)

sc-406616-LAChGene ActivationPuro, Blast, Hygro0
(0)

CD223 CRISPR Activation Plasmid (m)

sc-421371-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CD223 CRISPR Activation Plasmid (m2)

sc-421371-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CD223 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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CD223 siRNA (h)

sc-42836hGene SilencingN/A0
(0)

CD223 shRNA Plasmid (h)

sc-42836-SHhGene SilencingPuromycin0
(0)

CD223 shRNA (h) Lentiviral Particles

sc-42836-VhGene SilencingPuromycin0
(0)

CD223 siRNA (m)

sc-44548mGene SilencingN/A
1
(0)

CD223 shRNA Plasmid (m)

sc-44548-SHmGene SilencingPuromycin
1
(0)

CD223 shRNA (m) Lentiviral Particles

sc-44548-VmGene SilencingPuromycin
1
(0)