CCDC96 Activators
CCDC96 Activators encompass a diverse array of chemical compounds that indirectly enhance the functional activity of CCDC96 through modulation of specific signaling pathways and biological processes. Compounds like Forskolin and IBMX increase intracellular cAMP levels, subsequently activating PKA, which may phosphorylate proteins within the operational network of CCDC96, thus enhancing its functional activity. Similarly, Epigallocatechin gallate (EGCG), by altering kinase activity, and Sphingosine1-phosphate (S1P), through its receptor-mediated signaling, could indirectly enhance CCDC96 activity by affecting the cellular context in which CCDC96 functions. Anandamide's action on GPCRs and PMA's potent activation of PKC could change the phosphorylation landscape of proteins related to CCDC96, potentially increasing its activity. Meanwhile, U0126 and SB203580, by inhibiting the MAPK/ERK and p38 MAP kinase pathways respectively, might shift cellular signaling dynamics in a way that favors CCDC96 activation. LY294002's impact on the PI3K/Akt pathway could also create an environment conducive to CCDC96's enhanced activity by altering the signaling milieu.
Moreover, the presence of NAD+ can support the functional enhancement of CCDC96 by providing a substrate for enzymes that regulate DNA repair and signaling, thereby promoting a cellular environment where CCDC96's activity is potentially augmented. Resveratrol's effects on sirtuin activation and Zinc ions' role as a cofactor for various enzymes and transcription factors are another avenue through which CCDC96's activity could be indirectly increased, through the modulation of associated proteins and pathways. Collectively, these CCDC96 Activators exert their influence on a range of cellular signaling events and processes, which, although not directly activating CCDC96, create a biological context that is supportive of its enhanced functional activity without necessitating direct interaction with the protein or upregulation of its expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin is a labdane diterpene that functions as an adenylate cyclase activator, increasing levels of cyclic AMP (cAMP) in cells. Elevated cAMP in turn activates protein kinase A (PKA), which can phosphorylate various proteins that may be involved in the signaling pathways that CCDC96 is a part of, thus potentially enhancing the functional activity of CCDC96. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX (3-Isobutyl-1-methylxanthine) is a non-selective inhibitor of phosphodiesterases, leading to increased intracellular cAMP levels by preventing its breakdown. This action may enhance signaling pathways, including those regulated by PKA, which could indirectly increase the activity of CCDC96 by promoting the phosphorylation of proteins within CCDC96's functional network. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a polyphenol found in green tea with antioxidant properties. It is also known to modulate various signaling pathways, including those mediated by kinases. By altering kinase activity, EGCG could influence pathways that CCDC96 is part of, thereby enhancing its functional activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
S1P is a bioactive lipid that acts as a ligand for S1P receptors, initiating signaling cascades that regulate cell survival and proliferation. Its role in these pathways could indirectly enhance the activity of CCDC96 by modulating the cellular context in which CCDC96 operates. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC), which plays a role in various signaling pathways. Activation of PKC can lead to changes in phosphorylation patterns of proteins, potentially enhancing the activity of CCDC96 as part of these pathways. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is an inhibitor of MEK1/2, which are enzymes in the MAPK/ERK pathway. By inhibiting this pathway, U0126 might shift the balance of cellular signaling, potentially enhancing pathways that CCDC96 is involved in. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAP kinase. By inhibiting p38, it could modulate cellular stress responses, potentially favoring signaling pathways that activate CCDC96. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that can affect various signaling pathways, including Akt signaling. By modulating PI3K/Akt pathway activity, it could indirectly enhance the functional activity of CCDC96 by altering the signaling environment. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NAD+ is a coenzyme in redox reactions and a substrate for sirtuins and ADP-ribosyltransferases, which are involved in DNA repair and signaling. By influencing these processes, NAD+ may enhance the activity of CCDC96 by promoting a cellular environment conducive to its function. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a stilbenoid with antioxidant properties and can modulate various signaling pathways, including sirtuin activation. This modulation could indirectly enhance the activity of CCDC96 by influencing pathways and processes that CCDC96 is associated with. | ||||||