Date published: 2026-5-16

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CCDC129 Inhibitors

CCDC129 inhibitors encompass a chemical class designed to target the protein encoded by the Coil-Coiled Domain Containing 129 (CCDC129) gene. These inhibitors interact with the protein at a molecular level, obstructing its normal function within cellular processes. The CCDC129 protein typically plays a role in cellular structure and function, potentially involving the regulation of gene expression or the modulation of signal transduction pathways. Inhibitors targeting CCDC129 would, therefore, be expected to interfere with these processes. The exact mechanisms by which CCDC129 contributes to cellular function are not fully elucidated, but inhibitors in this class would likely be designed to bind to the protein's coiled-coil domain, a structural motif involved in protein-protein interactions. By doing so, these inhibitors would prevent CCDC129 from forming functional complexes with other proteins, thereby hindering its ability to carry out its normal biological roles. The chemical compounds that fall under the category of CCDC129 inhibitors would be characterized by their specificity in binding to the CCDC129 protein. This specificity is crucial, as it ensures that the inhibitors do not inadvertently affect other proteins with similar domains or functions. The design of CCDC129 inhibitors would be based on the understanding of the protein's structure, especially the coiled-coil domain that these compounds aim to target. Successful inhibition of CCDC129 could affect various downstream pathways that are regulated by the protein, leading to alterations in gene expression patterns or the disruption of signaling cascades that CCDC129 may be involved in. As research progresses, the specific biochemical pathways modulated by CCDC129 are expected to become clearer, which would, in turn, refine the development of these inhibitors to ensure they effectively achieve their intended purpose without off-target effects.

Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Y-27632 is a ROCK inhibitor which can modulate actin cytoskeleton dynamics and cell contraction. By inhibiting ROCK, Y-27632 may interfere with the cellular processes that lead to the activation or proper functioning of CCDC129.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Thapsigargin is a SERCA (sarcoplasmic/endoplasmic reticulum Ca2+ ATPase) pump inhibitor, leading to an increase in cytosolic calcium levels and potentially disturbing various calcium-dependent signaling pathways, which might affect proteins like CCDC129.