CCDC105 inhibitors are a diverse group of chemical compounds that interact with various signaling pathways, potentially leading to the inhibition of the CCDC105 protein's functional activity. These inhibitors work through different mechanisms to achieve this effect, often involving the modulation of kinase activity or the alteration of specific signaling pathways that are essential for the functional regulation of CCDC105.
Staurosporine and chelerythrine, for instance, target kinase activity directly, which is crucial for the phosphorylation-dependent regulation of many proteins, including CCDC105. Inhibition of these kinases might prevent the phosphorylation that is necessary for CCDC105 activation or interaction with other cellular components. Similarly, Go6983 and other PKC inhibitors like chelerythrine can disrupt PKC-mediated pathways, potentially affecting CCDC105's activity by altering its phosphorylation state.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, part of the MAPK pathway. Inhibition of JNK signaling could lead to decreased activity of transcription factors that regulate CCDC105, thus reducing its functional activity. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $199.00 $460.00 $1479.00 | 1 | |
NF449 is a potent and selective inhibitor of Gs-alpha subunit of G-proteins. If CCDC105 is regulated by G-protein-coupled receptor signaling through the Gs-alpha pathway, NF449 would lead to decreased G-protein signaling and consequently reduce CCDC105 activity. | ||||||