Calpain 1 Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Facilitates the transport of calcium ions across biological membranes. It has been shown to increase calpain 1 expression in various cell types. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $92.00 $240.00 $4328.00 | 9 | |
Arachidonic acid is an unsaturated fatty acid that can be released from cell membranes by phospholipase A2. It serves as a precursor for the synthesis of various bioactive compounds, including prostaglandins and leukotrienes. Arachidonic acid has been shown to upregulate calpain 1 expression. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin is a natural compound found in the plant Thapsia garganica. It is a potent inhibitor of the sarco/endoplasmic reticulum calcium ATPase (SERCA) pump, leading to calcium release from the endoplasmic reticulum. Thapsigargin treatment has been found to induce calpain 1 expression. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS is a component of the outer membrane of Gram-negative bacteria and is widely used to induce immune responses in experimental models. LPS treatment has been reported to upregulate calpain 1 expression in various cell types. | ||||||
CA 1001 | 58801-34-6 | sc-202512 | 25 mg | $163.00 | 2 | |
Calcium ionophores are compounds that increase intracellular calcium levels by facilitating the transport of calcium ions across biological membranes. They can activate calpain 1 and upregulate its expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a natural compound found in the Indian coleus plant (Coleus forskohlii). It stimulates the production of cyclic adenosine monophosphate (cAMP), which is involved in intracellular signaling. Forskolin treatment has been associated with an increase in calpain 1 expression. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
H2O2, or hydrogen peroxide, is a reactive oxygen species that can be generated during oxidative stress. Its presence can lead to the upregulation of calpain 1 expression in various cellular contexts. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC) and has been reported to induce calpain 1 expression. The mechanisms through which PMA influences calpain 1 expression may involve PKC-dependent signaling pathways. | ||||||