Date published: 2026-4-25

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Calcium Channel Modulators

Santa Cruz Biotechnology now offers a broad range of calcium channel modulators for use in various applications. Calcium channel modulators are crucial compounds in scientific research due to their ability to influence the activity of calcium channels, which are essential for numerous cellular processes including muscle contraction, neurotransmitter release, and gene expression. These modulators are utilized extensively in neurobiology, physiology, and cell biology to study the intricate mechanisms of calcium signaling pathways. Researchers employ calcium channel modulators to dissect the roles of specific calcium channels in various physiological and pathological contexts, enabling a deeper understanding of how these channels regulate cellular functions. Additionally, these compounds are valuable in the development of new experimental models for investigating the effects of altered calcium channel activity on cellular and systemic physiology. The ability to precisely modulate calcium channel activity allows scientists to explore the potential impacts on cellular homeostasis, signal transduction, and metabolic regulation. By providing a comprehensive selection of high-quality calcium channel modulators, Santa Cruz Biotechnology supports advanced research endeavors, facilitating the discovery of new insights into the fundamental processes governed by calcium signaling. These modulators enhance the capacity for innovative experimentation and the development of novel scientific methodologies. View detailed information on our available calcium channel modulators by clicking on the product name.

Items 161 to 167 of 167 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Nifedipine-d6

1188266-14-9sc-219373
1 mg
$306.00
(0)

Nifedipine-d6 acts as a calcium channel modulator by selectively interacting with L-type calcium channels, influencing their conformational states. This isotopically labeled variant exhibits unique kinetic properties, allowing for precise tracking in metabolic studies. Its deuterated structure enhances stability and alters reaction pathways, providing insights into calcium dynamics. The compound's distinct isotopic signature aids in elucidating the mechanisms underlying calcium-mediated cellular processes.

cis Lacidipine

103890-79-5sc-217905
1 mg
$340.00
(0)

Cis Lacidipine functions as a calcium channel modulator by preferentially binding to specific sites on L-type calcium channels, leading to altered channel gating dynamics. Its unique stereochemistry influences the interaction with lipid bilayers, enhancing membrane fluidity and affecting ion permeability. The compound exhibits distinct reaction kinetics, allowing for nuanced modulation of calcium influx, which can impact various cellular signaling pathways. Its structural characteristics facilitate targeted studies on calcium homeostasis and cellular excitability.

Verapamil-d6 Hydrochloride

sc-220374
sc-220374-CW
1 mg
5 mg
$357.00
$1571.00
4
(1)

Verapamil-d6 Hydrochloride acts as a calcium channel modulator by selectively interacting with L-type calcium channels, influencing their conformational states. The deuterated form enhances stability and alters isotopic effects, providing insights into reaction mechanisms. Its unique molecular structure promotes specific binding affinities, affecting the kinetics of calcium ion transport. This compound's behavior in lipid environments can reveal critical information about membrane interactions and ion channel dynamics.

Ryanodine

15662-33-6sc-201523
sc-201523A
1 mg
5 mg
$223.00
$799.00
19
(2)

Ryanodine functions as a calcium channel modulator by binding to ryanodine receptors, which are integral to calcium release from the sarcoplasmic reticulum. This interaction stabilizes the open state of the channel, leading to prolonged calcium ion flux. Its unique cyclic structure allows for specific molecular recognition, influencing the kinetics of calcium signaling pathways. Additionally, Ryanodine's distinct conformational flexibility can impact its binding dynamics and receptor activation profiles.

(-)-α-Benidipine Hydrochloride

129262-07-3sc-503305
1 mg
$540.00
(0)

(-)-α-Benidipine Hydrochloride exhibits distinctive calcium channel modulation through its unique stereochemistry, which enhances its binding affinity to L-type calcium channels. The compound's hydrophobic regions facilitate specific interactions with lipid membranes, influencing its permeability and distribution. Its dynamic conformational changes under varying ionic conditions can affect channel gating mechanisms, providing insights into the modulation of calcium influx in cellular processes.

Rhod-5N, tripotassium salt

sc-491374
1 mg
$315.00
(0)

Rhod-5N, tripotassium salt, exhibits remarkable properties as a calcium channel modulator through its ability to interact with lipid membranes and alter membrane potential. Its unique structure enables selective binding to calcium channels, influencing ion flow and cellular excitability. The compound's tripotassium form enhances its electrochemical stability, promoting efficient charge transfer. Additionally, its photostability allows for prolonged activity in dynamic environments, making it a versatile agent in biochemical pathways.

3′,4′-Dichlorobenzamil hydrochloride

928621-15-2sc-507264
5 mg
$265.00
(0)