Date published: 2026-5-28

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CA VI Inhibitors

CA VI inhibitors belong to a distinct chemical class that targets the enzyme carbonic anhydrase VI (CA VI). This class of inhibitors is specifically designed to interact with and modulate the activity of the CA VI enzyme, which plays a crucial role in catalyzing the reversible hydration of carbon dioxide. By inhibiting CA VI, these compounds disrupt its natural function, leading to the reduction of its enzymatic activity. The precise molecular structure of CA VI inhibitors allows them to bind to the active site of the enzyme, forming stable complexes that interfere with its normal catalytic function. This inhibition can be reversible or irreversible depending on the specific chemical properties of the inhibitor. As a consequence, the overall effect of CA VI inhibitors is a modulation of carbonic anhydrase activity, which may have significant implications in various biological processes. The exploration of CA VI inhibitors is an ongoing area of research in chemical biology and may hold potential applications in diverse fields, such as basic research, and chemical enzymology.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Dorzolamide Hydrochloride

130693-82-2sc-207596
10 mg
$186.00
(1)

Dorzolamide Hydrochloride is a sulfonamide compound that showcases intriguing reactivity due to its ability to form strong ionic interactions with surrounding molecules. Its unique sulfonyl group contributes to its polar character, enhancing its affinity for polar solvents. The compound's electronic structure allows for resonance stabilization, influencing its kinetic behavior in reactions. Additionally, its crystalline form exhibits distinct packing arrangements, affecting its dissolution rates and interactions in various media.

Acetazolamide

59-66-5sc-214461
sc-214461A
sc-214461B
sc-214461C
sc-214461D
sc-214461E
sc-214461F
10 g
25 g
100 g
250 g
500 g
1 kg
2 kg
$81.00
$177.00
$434.00
$541.00
$883.00
$1479.00
$2244.00
1
(1)

This is a well-known and widely used CA inhibitor that targets various isoforms, including CA VI.

Methazolamide

554-57-4sc-235615
1 g
$94.00
3
(1)

Similar to acetazolamide, methazolamide is a CA inhibitor studied in the research of glaucoma and certain types of edema.

Brinzolamide

138890-62-7sc-481649
10 mg
$269.00
(0)

Another CA VI inhibitor used as eye drops to lower intraocular pressure with glaucoma

Topiramate

97240-79-4sc-204350
sc-204350A
10 mg
50 mg
$107.00
$369.00
(1)

While primarily used as an anticonvulsant and for migraines, topiramate also exhibits inhibitory effects on CA VI.