Date published: 2025-12-18

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CA IV Inhibitors

Carbonic Anhydrase IV (CA IV) is an enzyme involved in catalyzing the reversible conversion of carbon dioxide and water into bicarbonate and protons. In the context of inhibiting CA IV, there is no dedicated chemical class that exclusively targets this particular enzyme. Inhibitors of carbonic anhydrase enzymes generally encompass a diverse range of chemical structures and classes. These inhibitors are designed to interact with the active site of carbonic anhydrase enzymes, disrupting their catalytic activity. The structural characteristics and mechanisms of inhibition can vary depending on the specific inhibitor compound and its chemical class. The inhibition of CA IV by these compounds is an area of ongoing research, aiming to understand the role of CA IV in various biological processes. The study of CA IV inhibitors contributes to the broader understanding of carbonic anhydrase enzymes and their physiological functions.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Topiramate

97240-79-4sc-204350
sc-204350A
10 mg
50 mg
$105.00
$362.00
(1)

Topiramate exhibits unique reactivity as a carbonic anhydrase inhibitor, engaging in specific molecular interactions that alter enzyme dynamics. Its structural conformation allows for selective binding, influencing catalytic efficiency and substrate turnover. The compound's ability to form stable complexes with metal ions enhances its role in coordination chemistry. Additionally, its solubility in diverse solvents facilitates exploration of reaction mechanisms, making it a valuable subject for kinetic studies.

Acetazolamide

59-66-5sc-214461
sc-214461A
sc-214461B
sc-214461C
sc-214461D
sc-214461E
sc-214461F
10 g
25 g
100 g
250 g
500 g
1 kg
2 kg
$79.00
$174.00
$425.00
$530.00
$866.00
$1450.00
$2200.00
1
(1)

It is a well-known inhibitor of Carbonic Anhydrase and is commonly used to decrease the production of aqueous humor in the eye.

Dorzolamide

120279-96-1sc-337687
1 g
$960.00
2
(0)

This is a specific inhibitor of Carbonic Anhydrase II, which is found in the ciliary body of the eye, and is used to reduce intraocular pressure in glaucoma.

Methazolamide

554-57-4sc-235615
1 g
$92.00
3
(1)

Similar to acetazolamide, methazolamide inhibits Carbonic Anhydrase enzymes, including Carbonic Anhydrase IV.

Brinzolamide

138890-62-7sc-481649
10 mg
$264.00
(0)

It is a topical Carbonic Anhydrase inhibitor used as eye drops to reduce intraocular pressure in glaucoma.

Furosemide

54-31-9sc-203961
50 mg
$40.00
(1)

While primarily known as a loop diuretic, furosemide also possesses Carbonic Anhydrase inhibitory activity, although it is less potent than some other specific inhibitors.