C8orf47 Inhibitors
C8orf47 inhibitors encompass a range of chemical compounds that act on specific signaling pathways, with the end result being a decrease in C8orf47 activity. The primary pathways targeted by these inhibitors include the PI3K/AKT, JNK, p38 MAPK, and MEK/ERK pathways. A majority of these compounds, such as resveratrol, LY294002, quercetin, genistein, wortmannin, apigenin, and EGCG, act on the PI3K/AKT pathway, a critical signaling pathway that C8orf47 is thought to interact with. By inhibiting this pathway, these compounds can effectively reduce the functional activity of C8orf47.
Other inhibitors target different but related pathways. For example, curcumin and SP600125 hinder the JNK and p38 MAPK pathways. Simultaneously, SB203580 acts on the p38 MAPK pathway, and PD98059 and U0126 inhibit the MAPK and MEK/ERK pathways, respectively. These pathways are believed to intersect with C8orf47's functional mechanisms. Consequently, these inhibitors can indirectly reduce C8orf47 activity by dampening the signaling pathways it is involved with.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is known to inhibit the PI3K/AKT pathway. This pathway's inhibition can lead to reduced activity of C8orf47, as the protein interacts indirectly with PI3K/AKT. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can impact the JNK and p38 MAPK signaling pathways, which C8orf47 is thought to interact with. Inhibiting these pathways via curcumin can decrease C8orf47 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a potent PI3K inhibitor, and by extension, inhibits the PI3K/AKT pathway. Given C8orf47's involvement in this pathway, this inhibition can result in lowered C8orf47 activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin can inhibit the PI3K/AKT pathway, which C8orf47 is known to interact with. Consequently, the inhibition of this pathway by quercetin can lead to a decrease in C8orf47 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of the MAPK pathway. As C8orf47 is believed to interface with this pathway, its inhibition by PD98059 can lead to decreased C8orf47 activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein inhibits the PI3K/AKT pathway, which C8orf47 is known to interact with. Therefore, its inhibition by genistein can result in reduced C8orf47 activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits the p38 MAPK pathway. If C8orf47 is involved in this pathway, its inhibition by SB203580 can result in decreased C8orf47 activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits the JNK pathway, which C8orf47 is thought to interact with. This inhibition can lead to decreased C8orf47 function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits PI3K and thus the PI3K/AKT pathway. As C8orf47 interacts with this pathway, its activity can be reduced by wortmannin's inhibitory effects. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin inhibits the PI3K/AKT pathway. As C8orf47 is known to interact with this pathway, the inhibitory effects of apigenin can result in reduced C8orf47 activity. | ||||||