Date published: 2026-4-5

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C1r Antibodies

Santa Cruz Biotechnology features a diverse variety of C1r monoclonal antibodies for research focused on understanding the complement system and its role in immune responses. C1r monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). C1r is a serine protease that plays a crucial role in the activation of the complement cascade, which is essential for opsonization, inflammation, and cell lysis. By cleaving C1s, C1r initiates the classical pathway of complement activation, highlighting its importance in both innate and adaptive immunity. Understanding the function of C1r is vital for elucidating mechanisms of immune regulation and potential therapeutic targets in various diseases. Researchers can utilize C1r monoclonal antibodies to investigate complement cascade activation pathways and their implications in immune responses. C1r monoclonal antibodies enable detailed examination of protein-protein interactions within the complement system. Exploring C1r's role in disease progression and immune regulation can lead to new therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies for C1r support researchers worldwide in advancing our understanding of complement biology and immune system function.

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C1r Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

C1r Antibody (F-7)

sc-514105mouse IgG2b κ192-216 (h)WB, IP, IF, ELISAm, r, h
4
(8)

C1r Antibody (F-1)

sc-271642mouse IgG1 κ188-313 (h)WB, IP, IF, ELISAh

new

(1)

C1r CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

C1r CRISPR/Cas9 KO Plasmid (h)

sc-405842hGene KnockoutGFP0
(0)

C1r Double Nickase Plasmid (h)

sc-405842-NIChGene KnockoutPuromycin0
(0)

C1r Double Nickase Plasmid (h2)

sc-405842-NIC-2hGene KnockoutPuromycin0
(0)

C1s Double Nickase Plasmid (h)

sc-404794-NIChGene KnockoutPuromycin0
(0)

C1s Double Nickase Plasmid (h2)

sc-404794-NIC-2hGene KnockoutPuromycin0
(0)

C1r CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

C1s CRISPR Activation Plasmid (h)

sc-404794-ACThGene ActivationPuro, Blast, Hygro0
(0)

C1r siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

C1r siRNA (h)

sc-60299hGene SilencingN/A0
(0)

C1r shRNA Plasmid (h)

sc-60299-SHhGene SilencingPuromycin0
(0)

C1r shRNA (h) Lentiviral Particles

sc-60299-VhGene SilencingPuromycin0
(0)

C1r siRNA (m)

sc-60300mGene SilencingN/A0
(0)

C1r shRNA Plasmid (m)

sc-60300-SHmGene SilencingPuromycin0
(0)

C1r shRNA (m) Lentiviral Particles

sc-60300-VmGene SilencingPuromycin0
(0)

C1s siRNA (h)

sc-60301hGene SilencingN/A0
(0)

C1s shRNA Plasmid (h)

sc-60301-SHhGene SilencingPuromycin0
(0)

C1s shRNA (h) Lentiviral Particles

sc-60301-VhGene SilencingPuromycin0
(0)

C1s siRNA (m)

sc-60302mGene SilencingN/A0
(0)

C1s shRNA Plasmid (m)

sc-60302-SHmGene SilencingPuromycin0
(0)

C1s shRNA (m) Lentiviral Particles

sc-60302-VmGene SilencingPuromycin0
(0)

C1sb siRNA (m)

sc-141849mGene SilencingN/A0
(0)

C1sb shRNA Plasmid (m)

sc-141849-SHmGene SilencingPuromycin0
(0)

C1sb shRNA (m) Lentiviral Particles

sc-141849-VmGene SilencingPuromycin0
(0)