C1r Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
p-APMSF, Hydrochloride | 74938-88-8 | sc-204155 sc-204155A sc-204155B sc-204155C | 5 mg 10 mg 50 mg 100 mg | $87.00 $111.00 $305.00 $571.00 | 1 | |
p-APMSF, Hydrochloride acts as a potent c1r inhibitor, characterized by its ability to form stable complexes through electrostatic and hydrophobic interactions. This compound exhibits a unique reactivity profile, facilitating selective acylation of target residues, which alters enzymatic activity. Its solubility in polar solvents enhances its diffusion across membranes, allowing for rapid engagement with biological targets. The compound's distinct steric properties influence its binding kinetics, leading to significant modulation of cellular signaling pathways. | ||||||
Sivelestat | 127373-66-4 | sc-203938 | 1 mg | $105.00 | 2 | |
A neutrophil elastase inhibitor that can indirectly reduce the activation of the complement system by limiting the release of elastase, which can modulate complement activity. | ||||||
Nafamostat mesylate | 82956-11-4 | sc-201307 sc-201307A | 10 mg 50 mg | $82.00 $306.00 | 4 | |
A serine protease inhibitor that can indirectly affect C1R activity by inhibiting factors such as kallikrein, which are involved in the complement activation pathway. | ||||||
Tranexamic acid | 1197-18-8 | sc-204921 sc-204921A | 5 g 10 g | $29.00 $50.00 | 10 | |
An antifibrinolytic that may indirectly influence C1R by stabilizing fibrin and preventing plasminogen activation, which can modulate the complement system. | ||||||
Andrographolide | 5508-58-7 | sc-205594 sc-205594A | 50 mg 100 mg | $15.00 $40.00 | 7 | |
A labdane diterpenoid that is known to have anti-inflammatory properties and may indirectly influence C1R activity through modulation of the complement pathway. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
An isoquinoline alkaloid that has been reported to have complement-inhibitory activities, potentially affecting C1R indirectly by stabilizing the complement system. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol from green tea that has been reported to interfere with the complement cascade, possibly affecting C1R indirectly by inhibiting the conversion of C3 to C3a and C3b. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A natural phenolic compound that may modulate the immune response and indirectly inhibit C1R by affecting multiple points in the complement pathway. | ||||||