C1qL3 Activators

C1qL3, also known as Complement Component 1q Like Protein 3, is a gene that encodes a protein associated with the complement system, a critical part of the innate immune system. The complement system consists of a group of proteins that play pivotal roles in defending the body against infections, clearing damaged cells, and regulating inflammatory responses.C1qL3 belongs to the C1q/TNF-related protein (CTRPs) family, a group of secreted proteins with diverse functions. While C1qL3 shares structural similarities with the C1q complement protein, it does not appear to be directly involved in the classical complement activation pathway. Instead, C1qL3 has been implicated in various physiological processes.One of the notable functions of C1qL3 is its role in metabolism and energy homeostasis. It is primarily secreted by adipose (fat) tissues and has been shown to influence insulin sensitivity and glucose metabolism. Research suggests that C1qL3 may act as an adipokine, a signaling molecule produced by adipose tissue, and play a role in regulating metabolism, obesity, and related metabolic disorders.

C1qL3 has also been associated with tissue remodeling and fibrosis. It is involved in regulating the function of fibroblasts and the remodeling of the extracellular matrix, processes essential for wound healing and tissue regeneration. Dysregulation of C1qL3 has been linked to pathological conditions characterized by excessive tissue fibrosis.Studies on C1qL3 are ongoing to uncover its precise mechanisms of action and its implications in various diseases. Understanding its functions in metabolism, tissue repair, and immune regulation may offer insights into strategies for metabolic disorders, fibrosis, and other related conditions.