Date published: 2026-5-15

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C17orf28 Inhibitors

C17orf28 inhibitors like Wortmannin and SB203580, by inhibiting key kinases in the PI3K/Akt and MAPK pathways respectively, can modify the phosphorylation state of numerous proteins, potentially including C17orf28. PD173074 and SP600125 may also attenuate growth factor and stress response pathways, influencing C17orf28 indirectly. ZM-447439's action on cell cycle kinases could affect C17orf28 if it has roles in cell division.

Compounds such as 5-Azacytidine and Trichostatin A target epigenetic regulators, potentially altering the transcription and expression patterns of genes like C17orf28. Tunicamycin and Brefeldin A disrupt protein modification and trafficking, potentially impacting the maturation and localization of C17orf28. Cycloheximide inhibits protein synthesis broadly, which can reduce the cellular levels of C17orf28. FK506's inhibition of calcineurin may affect proteins involved in immunological processes, which could include C17orf28 if it has a role in such pathways. 2-Deoxy-D-glucose's interference with glycolysis can have wide-reaching effects on cellular metabolism and energy-dependent processes, possibly affecting proteins like C17orf28 that may rely on these metabolic pathways.

SEE ALSO...

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Inhibits PI3K, potentially affecting C17orf28 if it is involved in the PI3K/Akt signaling pathway.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAP kinase, potentially affecting C17orf28 if it is regulated by the MAPK pathway.

PD173074

219580-11-7sc-202610
sc-202610A
sc-202610B
1 mg
5 mg
50 mg
$47.00
$143.00
$680.00
16
(1)

FGFR inhibitor that can affect growth factor signaling, potentially affecting C17orf28 activity.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits JNK, which could alter signaling pathways influencing C17orf28's function.

ZM-447439

331771-20-1sc-200696
sc-200696A
1 mg
10 mg
$153.00
$356.00
15
(1)

Aurora kinase inhibitor, potentially affecting C17orf28 if it is involved in cell cycle regulation.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

DNA methyltransferase inhibitor, potentially affecting gene expression of C17orf28.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

HDAC inhibitor that can alter chromatin structure and gene expression, possibly affecting C17orf28.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Inhibits N-linked glycosylation, potentially affecting C17orf28 if it undergoes glycosylation.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Disrupts protein trafficking by inhibiting Golgi function, potentially affecting C17orf28 localization.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Inhibits protein synthesis, potentially reducing overall levels of C17orf28.