C16orf91 Activators
Forskolin and Ionomycin increase the levels of cAMP and intracellular calcium, respectively, which act as secondary messengers in various signaling pathways. The activation of these pathways can lead to the phosphorylation of proteins and the initiation of a cascade of downstream effects that can modulate protein function. PMA and compounds such as Trichostatin A and Sodium Butyrate alter the activity of enzymes like PKC and HDAC, respectively, which are key modulators of protein phosphorylation and gene expression.
5-Azacytidine and Lithium Chloride exert their effects at the genetic level, influencing DNA methylation and Wnt signaling. LY294002, Rapamycin, and SB431542 specifically target key signaling molecules like PI3K, mTOR, and TGF-β receptors, which are central to the regulation of protein synthesis, autophagy, and SMAD signaling. PD98059 and DAPT interfere with the MAPK/ERK pathway and Notch signaling, respectively, both of which are crucial for the regulation of protein activity and cellular differentiation processes.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Increases intracellular calcium levels, which can activate calcium-dependent protein kinases and potentially influence proteins that are regulated by calcium signaling. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), which can modulate the phosphorylation and activity of proteins within related signaling cascades. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibits histone deacetylases (HDACs), leading to changes in chromatin structure and gene expression, which can influence protein synthesis. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferases, causing hypomethylation of DNA, which can alter gene expression patterns and potentially enhance protein production. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3β, which can activate Wnt signaling and potentially lead to increased expression and activity of proteins within this pathway. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Inhibits HDACs, leading to hyperacetylation of histones, which can affect gene expression and potentially increase protein synthesis. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K, which can modulate the AKT signaling pathway and potentially affect the activity of proteins regulated by AKT phosphorylation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, which can affect protein synthesis and autophagy pathways, potentially influencing the levels and activity of a wide range of proteins. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits the TGF-β receptor, which can modulate SMAD signaling pathways and potentially influence proteins regulated by this pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Inhibits MEK, which can affect the MAPK/ERK pathway and potentially alter the activity of proteins regulated by ERK-mediated phosphorylation. | ||||||