C14orf80 Activators
C14orf80, a protein associated with the tubulin epsilon and delta complex 1, has its functional activity influenced by compounds that target the microtubule structures within the cell. Certain molecules that stabilize microtubules and prevent their disassembly contribute to the enhancement of C14orf80 activity by maintaining the integrity of the microtubule network it binds to. Conversely, agents that disrupt microtubule assembly or inhibit polymerization also play a role in the indirect activation of C14orf80. The cellular response to such destabilization often involves an upregulation of microtubule-associated proteins, which may include C14orf80, to counteract the introduced instability and restore microtubule dynamics.
The intricate balance of microtubule stability is critical for cellular processes, and the disruption of this balance by various compounds can inadvertently lead to increased activity of proteins involved in microtubule stabilization, such as C14orf80. The compensatory mechanisms activated by the cell in response to such disruption may result in an upsurge in the functional activity of C14orf80. This protein plays a role in maintaining microtubule dynamics, and its activity is thus indirectly influenced by the action of compounds that either inhibit microtubule growth or enhance their stabilization, ensuring that the microtubule architecture remains functional despite the chemical perturbations.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
This compound stabilizes microtubules and prevents their disassembly, which can enhance the functional activity of C14orf80 by maintaining the microtubule structure it binds to. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
By binding to tubulin and inhibiting microtubule polymerization, colchicine can upregulate compensatory mechanisms that include the activation of C14orf80 to stabilize microtubule dynamics. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine disrupts microtubule assembly. The cellular response to this disruption can result in increased activity of microtubule-associated proteins like C14orf80 to restore stability. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
As a microtubule-depolymerizing agent, nocodazole can cause an upregulation of microtubule-stabilizing proteins, potentially including C14orf80, to counterbalance the destabilization. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Epothilone B stabilizes microtubules and can lead to a compensatory increase in the activity of microtubule-associated proteins such as C14orf80. | ||||||
Docetaxel | 114977-28-5 | sc-201436 sc-201436A sc-201436B | 5 mg 25 mg 250 mg | $85.00 $325.00 $1072.00 | 16 | |
Docetaxel stabilizes microtubules and can indirectly increase the activity of C14orf80 by preserving the microtubule structure it associates with. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
By inhibiting microtubule assembly, podophyllotoxin can activate cellular mechanisms that upregulate proteins like C14orf80 that stabilize microtubule dynamics. | ||||||
Eribulin | 253128-41-5 | sc-507547 | 5 mg | $865.00 | ||
Eribulin inhibits microtubule growth, which may enhance the activity of microtubule-associated proteins, including C14orf80, to compensate for disrupted microtubule dynamics. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Griseofulvin disrupts microtubule function by binding to tubulin, which can indirectly increase the activity of C14orf80 as the cell attempts to stabilize the microtubule network. | ||||||