C/EBP δ inhibitors belong to a specific chemical class acknowledged for their capacity to modulate the activity of CCAAT/enhancer-binding protein delta (C/EBP δ), a transcription factor that plays a significant role in regulating gene expression and cellular processes. These inhibitors function by interfering with the interactions involving C/EBP δ, which is involved in diverse cellular functions, including inflammation, metabolism, and differentiation. C/EBP δ acts as a transcriptional activator or repressor, modulating the expression of genes that influence various aspects of cellular physiology. C/EBP δ inhibitors are thoughtfully designed to target specific binding sites or molecular pathways associated with C/EBP δ, thus influencing its cellular functions and downstream effects.
The development of C/EBP δ inhibitors requires a comprehensive understanding of the structural attributes of C/EBP δ and its interactions with DNA and co-regulatory proteins. Researchers in this field strive to engineer molecules with high selectivity and affinity for C/EBP δ, allowing for precise modulation of its activities. These inhibitors often employ innovative design strategies that disrupt key molecular interactions necessary for C/EBP δ's functional role in gene expression regulation. By gaining insights into the intricate mechanisms through which C/EBP δ participates in diverse cellular processes, researchers aim to unravel its significance in fundamental biological phenomena. Ongoing advancements in molecular pharmacology and chemical synthesis drive the refinement of C/EBP δ inhibitors, offering applications across diverse scientific contexts where manipulation of C/EBP δ-mediated processes is of interest.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Troglitazone | 97322-87-7 | sc-200904 sc-200904B sc-200904A | 5 mg 10 mg 25 mg | $110.00 $204.00 $435.00 | 9 | |
Troglitazone inhibits C/EBP δ by activating PPARγ, which competes for binding with C/EBP δ at target gene promoters, reducing its transcriptional activity and downstream pro-inflammatory effects. | ||||||
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $82.00 $179.00 | 28 | |
GW501516 activates PPARδ to antagonize C/EBP δ-mediated transcription, thus suppressing pro-inflammatory cytokine expression, indicating potential therapeutic use in inflammation-related disorders. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A attenuates C/EBP δ function by affecting its DNA-binding ability, leading to reduced pro-inflammatory gene expression, making it a potential anti-inflammatory compound. | ||||||
T0070907 | 313516-66-4 | sc-203287 | 5 mg | $141.00 | 1 | |
T0070907 inhibits C/EBP δ by blocking its transcriptional activity through PPARγ activation, potentially counteracting inflammatory processes and offering therapeutic potential. | ||||||
GQ-16 | 870554-67-9 | sc-364377 sc-364377A | 5 mg 10 mg | $51.00 $97.00 | ||
GQ-16 antagonizes C/EBP δ function by targeting PPARδ activation, potentially reducing its pro-inflammatory effects and providing a basis for anti-inflammatory drug development. | ||||||
L-165041 | 79558-09-1 | sc-203094 | 5 mg | $156.00 | ||
L-165041 attenuates C/EBP δ activity by activating PPARγ, leading to diminished pro-inflammatory gene expression, which could be beneficial in the context of inflammation-related diseases. | ||||||
Telmisartan | 144701-48-4 | sc-204907 sc-204907A | 50 mg 100 mg | $72.00 $94.00 | 8 | |
Telmisartan modulates C/EBP δ by activating PPARγ, potentially reducing its pro-inflammatory effects and suggesting its application as an anti-inflammatory agent. | ||||||
GW 0742 | 317318-84-6 | sc-203991 sc-203991A | 10 mg 50 mg | $194.00 $831.00 | 11 | |
GW0742 targets PPARδ activation, which in turn inhibits C/EBP δ-mediated gene expression, potentially providing therapeutic benefits in inflammation-related disorders. | ||||||