Date published: 2025-12-17

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BRE Inhibitors

BRE inhibitors constitute a class of chemical compounds that have garnered attention in the field of molecular biology and gene expression research. These inhibitors are specifically designed to target and modulate the activity of BRE, which stands for Brain and Reproductive Organ-Expressed protein. BRE is a relatively newly discovered protein that has been implicated in various cellular processes, including transcriptional regulation and cellular stress responses. While the exact functions of BRE are still under investigation, it is known to interact with key transcriptional regulators, such as RNA polymerase II and transcription factor IIB (TFIIB), suggesting a role in the regulation of gene expression.

BRE inhibitors exert their effects by interfering with the function or expression of BRE, disrupting its role in transcriptional control and stress responses. This interference can lead to alterations in gene expression patterns and cellular responses to various stressors, influencing cellular physiology and homeostasis. Researchers employ BRE inhibitors as valuable tools to investigate the specific roles of BRE in different cellular contexts and to gain insights into the molecular mechanisms governing gene expression and stress responses. While the precise applications and broader implications of BRE inhibitors are subjects of ongoing research, their utility in elucidating the intricacies of transcriptional regulation and cellular stress responses is of paramount importance in advancing our understanding of molecular and cell biology.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

A histone deacetylase inhibitor, potentially altering chromatin structure and affecting gene expression, including BRE.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$36.00
$149.00
11
(1)

An antimetabolite that interferes with DNA synthesis, which could indirectly downregulate BRE expression.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Inhibits DNA topoisomerase I, leading to DNA damage and potential alterations in DNA repair gene expression like BRE.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Targets DNA topoisomerase II, disrupting DNA repair mechanisms which could affect BRE levels indirectly.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$206.00
$299.00
$485.00
10
(1)

A PARP inhibitor, potentially altering DNA repair pathways and indirectly affecting BRE expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

A compound with various cellular targets that may modulate transcription factor activity, potentially influencing BRE expression.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

A cyclin-dependent kinase inhibitor that can affect cell cycle progression and gene expression, including BRE.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

An isothiocyanate that activates Nrf2, potentially influencing the expression of DNA repair genes like BRE.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

A flavonoid that may impact signal transduction and gene regulation, potentially altering BRE expression.

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$52.00
$87.00
7
(1)

An aldehyde dehydrogenase inhibitor that can modulate various cellular pathways, potentially influencing BRE levels.