Date published: 2025-12-9

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Biotin Derivatives

Santa Cruz Biotechnology now offers a broad range of biotin derivatives for use in various applications. Biotin derivatives, which are chemically modified forms of biotin, have become indispensable tools in scientific research due to their strong affinity for streptavidin and avidin proteins. This high-affinity interaction is exploited in a variety of applications, including bioconjugation, labeling, and purification processes. In molecular biology, biotin derivatives are commonly used to label nucleic acids and proteins, facilitating their detection and isolation in experiments such as Western blotting, ELISA, and immunoprecipitation. These derivatives also play a critical role in developing biotin-streptavidin systems for affinity purification, which are essential for purifying proteins, nucleic acids, and other bioconjugates with high specificity and efficiency. In cell biology, biotinylated molecules are used to study cell surface interactions, receptor binding, and signal transduction pathways, providing insights into cellular mechanisms and functions. Environmental scientists utilize biotin derivatives in biosensor technologies to detect and quantify pollutants and other environmental contaminants, contributing to environmental monitoring and protection efforts. Additionally, in nanotechnology and materials science, biotin derivatives are employed to functionalize nanoparticles and other materials, enabling the development of advanced diagnostic tools and smart materials with tailored properties. By offering a diverse selection of biotin derivatives, Santa Cruz Biotechnology supports a wide range of scientific endeavors, enabling researchers to select the appropriate derivative for their specific experimental needs. This extensive range of biotin derivatives facilitates innovation and discovery across multiple scientific disciplines, including chemistry, biology, environmental science, and materials science. View detailed information on our available biotin derivatives by clicking on the product name.

Items 111 to 118 of 118 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(+)-Biotin Methyl Ester

608-16-2sc-503565
10 mg
$388.00
(0)

(+)-Biotin Methyl Ester is a distinctive biotin derivative featuring a methyl ester functional group that enhances its lipophilicity and membrane permeability. This compound exhibits unique molecular interactions with carboxylate groups, promoting esterification reactions. Its reactivity profile allows for efficient conjugation with various biomolecules, influencing metabolic pathways. The compound's stability under physiological conditions supports its role in modulating biochemical processes, making it a versatile tool in biochemical research.

Biotin Diacid

57671-79-1sc-503566
sc-503566A
sc-503566B
10 mg
25 mg
50 mg
$2400.00
$4000.00
$6005.00
(0)

Biotin Diacid is a notable biotin derivative characterized by its dual carboxylic acid groups, which facilitate strong hydrogen bonding and ionic interactions. This compound exhibits enhanced solubility in aqueous environments, promoting its reactivity in esterification and amidation reactions. Its unique structural features enable selective binding to proteins, influencing enzymatic activity and metabolic regulation. The compound's stability and reactivity make it a significant player in biochemical pathways.

D-Biotin Dimer Acid

1163708-46-0sc-503568
10 mg
$13500.00
(0)

D-Biotin Dimer Acid is a distinctive biotin derivative featuring a unique dimeric structure that enhances its capacity for molecular recognition. The compound's carboxylic acid functionalities enable it to engage in diverse electrostatic interactions, promoting its role in complexation with metal ions. Its reactivity profile is marked by rapid ester formation, allowing for versatile applications in synthetic chemistry. Additionally, its hydrophilic nature contributes to its behavior in biological systems, influencing solubility and transport mechanisms.

6-[4′-N-(biotinylaminopropyl-NHCOCH2-PEG2-acetyl)-aminophenyl]-hexane-2,4-dione

1522299-17-7sc-503571
5 mg
$380.00
(0)

6-[4'-N-(biotinylaminopropyl-NHCOCH2-PEG2-acetyl)-aminophenyl]-hexane-2,4-dione is a sophisticated biotin derivative characterized by its multifunctional structure, which facilitates specific binding interactions. The presence of a PEG spacer enhances solubility and biocompatibility, while the hexane-2,4-dione moiety introduces unique reactivity, allowing for selective conjugation with various biomolecules. This compound's design promotes efficient molecular assembly and targeted delivery in complex biological environments.

N-Biotinyl Dopamine

241142-94-9sc-503572
sc-503572A
10 mg
100 mg
$296.00
$2040.00
(0)

N-Biotinyl Dopamine is a versatile biotin derivative distinguished by its unique ability to engage in specific molecular interactions through its dopamine moiety. This compound exhibits enhanced stability and reactivity, enabling it to participate in diverse biochemical pathways. Its structural features facilitate the formation of dynamic complexes, promoting effective binding to target molecules. The integration of biotin enhances its affinity for avidin or streptavidin, making it a valuable tool for studying protein interactions and cellular processes.

10-Benzyloxyethoxyphosphinyl-N-biotinamidopentyldecanamide

1246814-51-6sc-503724
2.5 mg
$330.00
(0)

10-Benzyloxyethoxyphosphinyl-N-biotinamidopentyldecanamide is a distinctive biotin derivative characterized by its phosphinyl group, which enhances its reactivity and facilitates unique molecular interactions. This compound exhibits a robust capacity for forming stable conjugates, allowing for selective targeting in biochemical assays. Its structural design promotes efficient binding to biotin-binding proteins, enabling intricate studies of molecular dynamics and cellular mechanisms.

Biotinyl Tyramide

41994-02-9sc-503573
100 mg
$400.00
(1)

Biotinyl Tyramide is a biotin derivative characterized by its unique tyramide structure, which enhances its reactivity through the formation of covalent bonds with amine groups in proteins. This compound exhibits a high affinity for biotin-binding proteins, facilitating specific molecular interactions that can influence cellular pathways. Its distinct properties allow for efficient labeling and detection in various biochemical assays, showcasing its role in enhancing signal amplification through enzymatic reactions.

N-Biotinyl p-Aminophenyl Arsinic Acid

212391-23-6sc-503570B
sc-503570
sc-503570A
sc-503570C
sc-503570D
2 mg
5 mg
10 mg
25 mg
50 mg
$199.00
$352.00
$617.00
$1385.00
$2453.00
(0)

N-Biotinyl p-Aminophenyl Arsinic Acid is a biotin derivative characterized by its unique arsinic acid moiety, which facilitates specific interactions with biomolecules. This compound exhibits distinct reactivity patterns, particularly in nucleophilic substitution reactions, due to the presence of the amino group. Its structural features enable selective binding to proteins, potentially influencing cellular pathways. Additionally, its solubility in polar solvents enhances its compatibility in diverse chemical environments, affecting its overall behavior in various applications.