BFZB inhibitors are a class of chemical compounds that specifically target the BFZB protein, a member of a family of proteins involved in various cellular regulatory processes. BFZB, though not as well-characterized as some other regulatory proteins, is believed to play a role in transcriptional regulation and intracellular signaling pathways. These inhibitors are designed to block the functional domains of BFZB, preventing its interaction with other cellular components and disrupting its involvement in key cellular activities. BFZB is thought to participate in regulating gene expression and modulating signal transduction, making it a point of interest for researchers studying cellular mechanisms and protein-protein interactions. The inhibition of BFZB provides a tool to better understand its function and the downstream effects of its activity within the cell.
BFZB inhibitors are small molecules that bind to specific regions of the BFZB protein, particularly those involved in its binding and regulatory functions. By occupying these active sites, the inhibitors prevent BFZB from interacting with other proteins or DNA, thereby modulating its influence on cellular processes. Researchers use these inhibitors to explore how BFZB contributes to various biological pathways, particularly in the context of transcriptional regulation and signal processing. BFZB inhibitors offer a way to investigate the molecular structure and behavior of this protein, enabling insights into its role in broader cellular functions. They are critical tools for expanding our knowledge of how BFZB influences cellular regulation and for dissecting the complex networks of interactions in which this protein is involved.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA and prevents the transcription of mRNA, potentially reducing BFZB expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin inhibits RNA polymerase II, which is essential for mRNA synthesis, thereby potentially decreasing BFZB protein levels. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide has been shown to inhibit transcription by NF-κB, potentially downregulating BFZB if it is NF-κB-responsive. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II phosphorylation, potentially leading to reduced transcription of the BFZB gene. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Camptothecin stabilizes the DNA-topoisomerase I complex, potentially causing DNA damage and reducing BFZB expression. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide blocks the translocation step in protein synthesis, potentially decreasing the translation of BFZB mRNA. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine can elevate endosomal pH, which might interfere with the post-translational modification of BFZB. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, which could lead to a decrease in cap-dependent translation, possibly lowering BFZB levels. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin interferes with peptide bond formation at the ribosome, potentially inhibiting BFZB protein synthesis. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, potentially decreasing nucleotide availability for BFZB mRNA synthesis. | ||||||