BCLAF1 Inhibitors
BCLAF1 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of the BCLAF1 protein. BCLAF1, or BCL2-associated transcription factor 1, is a multifunctional protein involved in various cellular processes, primarily in the regulation of gene expression and RNA metabolism. It plays a crucial role in RNA splicing, transcriptional regulation, and mRNA stability, making it an intriguing target for research in various biological contexts. BCLAF1 inhibitors are designed to interact with this protein, either by binding to it directly or by interfering with its function, with the ultimate aim of influencing cellular processes governed by BCLAF1.
These inhibitors are of significant interest in the field of molecular biology and cell biology, as they offer a means to investigate the intricate regulatory mechanisms controlled by BCLAF1. By selectively inhibiting its activity, researchers can gain insights into how BCLAF1 contributes to mRNA processing, gene expression, and cellular responses to various stimuli. Understanding the role of BCLAF1 and its inhibition can shed light on fundamental biological processes and potentially reveal novel pathways that could be harnessed for future research purposes.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine can inhibit protein kinases that may phosphorylate Bclaf1, altering its activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine can alter gene expression patterns, potentially affecting Bclaf1 expression levels. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, Trichostatin A can modulate chromatin structure and potentially influence Bclaf1-related transcription. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibitor of JNK, which may phosphorylate substrates like Bclaf1 and regulate its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that can affect signaling pathways involving Bclaf1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An MEK inhibitor that could affect MAPK/ERK signaling, potentially influencing Bclaf1 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Another MEK inhibitor with a similar potential effect on Bclaf1 activity via the MAPK/ERK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
This p38 MAPK inhibitor can impact stress response pathways in which Bclaf1 may be involved. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor that can affect protein degradation, potentially stabilizing Bclaf1. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $62.00 $225.00 $779.00 | 24 | |
As an MDM2 antagonist, Nutlin-3 can stabilize p53, which may regulate genes associated with Bclaf1. | ||||||