BC100530 Activators
Cstdc5, also known as Cystatin Domain Containing 5, encodes a protein predicted to exhibit cysteine-type endopeptidase inhibitor activity and protease binding activity. This protein is implicated in processes such as keratinocyte differentiation, negative regulation of peptidase activity, and peptide cross-linking. The presence of a cystatin domain suggests a potential role in the inhibition of cysteine proteases, enzymes crucial for various cellular processes, including apoptosis, immune response, and extracellular matrix remodeling. The localization of Cstdc5 in cellular components such as the cornified envelope, extracellular space, and nucleoplasm underscores its diverse functions within the cell. The activation mechanisms of Cstdc5 remain to be fully elucidated. Given its predicted functions as a cysteine-type endopeptidase inhibitor and protease binder, it is plausible that its activation may involve specific signaling pathways responding to cellular stress, differentiation cues, or inflammatory stimuli. The regulation of Cstdc5 activity may be modulated by post-translational modifications or interactions with other proteins, ultimately influencing its inhibitory effect on cysteine proteases. Moreover, the involvement of Cstdc5 in keratinocyte differentiation implies a potential role in skin homeostasis and barrier function. The activation of Cstdc5 might be linked to signaling pathways regulating differentiation processes, possibly involving cascades like the MAPK pathway or other pathways known to modulate keratinocyte biology.
Investigations into the molecular partners of Cstdc5 and the specific events leading to its activation will be crucial in understanding its functional significance. Deciphering the intricate regulatory mechanisms governing Cstdc5's activity in different cellular contexts will contribute to our knowledge of its role in maintaining cellular homeostasis and may offer insights into its potential contributions to skin-related processes. Further experimental studies are needed to unravel the precise signaling events and cellular processes that activate Cstdc5, shedding light on its functional importance in cellular and tissue biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $281.00 $947.00 $1574.00 | 14 | |
Cysteine protease inhibitor potentially influencing Cstdc5. E-64 may directly impact Cstdc5 by inhibiting cysteine-type endopeptidases, altering its activity in cellular processes. Investigating the connection between E-64 and Cstdc5 sheds light on the regulation of cystatin domain-containing proteins and their involvement in keratinocyte differentiation and peptidase activity. | ||||||
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $73.00 $148.00 $316.00 $499.00 $1427.00 $101.00 | 19 | |
Protease inhibitor potentially affecting Cstdc5 activation. Leupeptin may directly or indirectly modulate Cstdc5 by inhibiting various proteases, impacting its role in peptidase activity and keratinocyte differentiation. Unraveling the connections between Leupeptin and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their cellular functions. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Cation potentially influencing Cstdc5 activation. Zinc sulfate may directly or indirectly modulate Cstdc5 through its impact on cellular processes, including peptide cross-linking. Investigating the connection between Zinc Sulfate and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in cellular functions related to the extracellular space and nucleoplasm. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid may indirectly activate Cstdc5 by influencing keratinocyte differentiation. Retinoic acid's role in regulating gene expression during keratinocyte differentiation can impact Cstdc5 activity. Investigating the connection between Retinoic Acid and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in cellular processes related to skin development. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoid receptor modulator potentially impacting Cstdc5 activation. Dexamethasone may indirectly activate Cstdc5 by influencing glucocorticoid receptor signaling, altering its role in cellular processes. Investigating the connection between Dexamethasone and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in peptidase activity and keratinocyte differentiation. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol (Vitamin D3) may indirectly activate Cstdc5 by influencing keratinocyte differentiation. Vitamin D3's role in regulating gene expression during keratinocyte differentiation can impact Cstdc5 activity. Investigating the connection between Vitamin D3 and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in cellular processes related to skin development. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Green tea polyphenol potentially impacting Cstdc5 activation. EGCG may directly or indirectly modulate Cstdc5 by influencing protease activity and cellular processes. Investigating the connection between EGCG and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in peptidase activity and keratinocyte differentiation. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
Solvent potentially influencing Cstdc5 activation. Dimethyl sulfoxide (DMSO) may directly or indirectly modulate Cstdc5 through its impact on cellular processes, including keratinocyte differentiation. Investigating the connection between DMSO and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in skin development. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
HDAC inhibitor potentially affecting Cstdc5 activation. Butyrate may indirectly activate Cstdc5 by inhibiting histone deacetylases, altering its role in cellular processes, including keratinocyte differentiation. Investigating the connection between Butyrate and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in skin development. | ||||||
Urea | 57-13-6 | sc-29114 sc-29114A sc-29114B | 1 kg 2 kg 5 kg | $31.00 $43.00 $78.00 | 17 | |
Chaotropic agent potentially influencing Cstdc5 activation. Urea may directly or indirectly modulate Cstdc5 through its impact on cellular processes, including peptide cross-linking. Investigating the connection between Urea and Cstdc5 sheds light on the regulatory mechanisms governing cystatin domain-containing proteins and their involvement in skin development and extracellular space. | ||||||