BC068157 Activators
Prr36, a proline-rich protein, holds significant importance in cellular processes, yet its precise activation mechanisms are not fully elucidated. Investigating potential activators, either direct or indirect, provides insights into the regulatory networks governing proline-rich proteins. Resveratrol, a polyphenol known for SIRT1 activation, may indirectly influence Prr36 by altering acetylation patterns, impacting its activity. Inhibition of p38 MAPK by SB203580 can modulate Prr36 phosphorylation, suggesting a potential link between MAPK signaling and Prr36 activation. AICAR, an AMPK activator, holds promise in directly or indirectly activating Prr36, connecting AMPK activity with Prr36 modulation. Histone deacetylase inhibitor Trichostatin A may impact Prr36 through epigenetic modifications, highlighting the role of epigenetic regulation in proline-rich protein activation.
Additionally, PI3K inhibition by LY294002, mTOR inhibition by Rapamycin, and JNK inhibition by SP600125 may indirectly modulate Prr36, suggesting interconnected signaling pathways. Inhibition of MEK by PD98059 and Rac1 by NSC23766 could influence Prr36, emphasizing the cross-talk between MAPK and small GTPase signaling. DNA methyltransferase inhibition by 5-Azacytidine may suggest epigenetic control over Prr36 expression. Furthermore, SB431542, a TGF-β receptor inhibitor, and JSH-23, an NF-κB inhibitor, indicate potential interactions between Prr36 and these signaling pathways. Understanding the intricate interplay between these chemicals and Prr36 sheds light on the regulatory mechanisms governing proline-rich proteins in cellular homeostasis. Prr36 activation appears to be a dynamic process influenced by multiple interconnected signaling pathways, underscoring its crucial role in cellular responses and highlighting avenues for further exploration in the field of proline-rich protein regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Polyphenol with potential Prr36 activation by influencing the SIRT1 pathway. Resveratrol, an activator of SIRT1, may indirectly activate Prr36 through its role in deacetylating cellular proteins. This process can affect the acetylation status of Prr36, potentially modulating its activity and function. Understanding the interplay between SIRT1 activation and Prr36 sheds light on the regulation of proline-rich proteins and their involvement in cellular processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor potentially impacting Prr36 activation. SB203580 may indirectly modulate Prr36 by inhibiting the p38 MAPK pathway. This inhibition can alter the phosphorylation status of Prr36, influencing its activity. Investigating the cross-talk between p38 MAPK signaling and Prr36 activation provides insights into the regulatory mechanisms governing proline-rich proteins and their roles in cellular responses. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AMP-activated protein kinase (AMPK) activator influencing Prr36. AICAR may directly or indirectly activate Prr36 by modulating AMPK activity. The activation of AMPK can impact Prr36 through various cellular processes, potentially regulating its function. Unraveling the connections between AMPK activation and Prr36 sheds light on the intricate regulatory networks involving proline-rich proteins and their participation in cellular homeostasis. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase (HDAC) inhibitor potentially affecting Prr36. Trichostatin A may indirectly activate Prr36 by inhibiting HDACs, leading to altered acetylation patterns on histones and potentially affecting Prr36 expression or activity. Investigating the impact of HDAC inhibition on Prr36 sheds light on the epigenetic regulation of proline-rich proteins and their involvement in cellular processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor potentially affecting Prr36 activation. Rapamycin may indirectly modulate Prr36 by inhibiting mTOR, impacting downstream signaling pathways. This inhibition can alter Prr36 activity and its participation in cellular processes. Investigating the connections between mTOR inhibition and Prr36 sheds light on the regulatory mechanisms governing proline-rich proteins and their roles in cellular homeostasis. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor potentially impacting Prr36 activation. SP600125 may indirectly modulate Prr36 by inhibiting JNK, influencing downstream signaling pathways. This inhibition can alter Prr36 activity and its involvement in cellular processes. Unraveling the connections between JNK inhibition and Prr36 sheds light on the regulatory mechanisms governing proline-rich proteins and their roles in cellular responses. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor influencing Prr36 activation. PD98059 may indirectly modulate Prr36 by inhibiting MEK, impacting downstream signaling pathways. This inhibition can alter Prr36 activity and its participation in cellular processes. Investigating the connections between MEK inhibition and Prr36 sheds light on the regulatory mechanisms governing proline-rich proteins and their roles in cellular homeostasis. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor potentially influencing Prr36. 5-Azacytidine may indirectly modulate Prr36 by inhibiting DNA methylation, impacting gene expression patterns. This modulation can affect Prr36 activity and its involvement in cellular processes. Exploring the connections between DNA methylation inhibition and Prr36 sheds light on the epigenetic regulation of proline-rich proteins and their roles in cellular responses. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
TGF-β receptor inhibitor potentially impacting Prr36 activation. SB431542 may indirectly modulate Prr36 by inhibiting TGF-β receptor signaling, altering downstream pathways. This inhibition can influence Prr36 activity and its involvement in cellular processes. Exploring the connections between TGF-β receptor inhibition and Prr36 sheds light on the regulatory mechanisms governing proline-rich proteins and their roles in cellular responses. | ||||||
NFκB Activation Inhibitor II, JSH-23 | 749886-87-1 | sc-222061 sc-222061C sc-222061A sc-222061B | 5 mg 10 mg 50 mg 100 mg | $210.00 $252.00 $1740.00 $1964.00 | 34 | |
NF-κB inhibitor potentially affecting Prr36 activation. JSH-23 may indirectly modulate Prr36 by inhibiting NF-κB signaling, influencing downstream pathways. This inhibition can alter Prr36 activity and its participation in cellular processes. Investigating the connections between NF-κB inhibition and Prr36 sheds light on the regulatory mechanisms governing proline-rich proteins and their roles in cellular homeostasis. | ||||||