Date published: 2025-10-15

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Axin Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Axin monoclonal antibodies for investigating cellular signaling pathways. Axin monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).Axin is a key component of the Wnt signaling pathway, which is essential for regulating cell proliferation, differentiation, and embryonic development. As a scaffold protein, Axin facilitates the degradation of β-catenin, thereby controlling the transcription of Wnt target genes. Dysregulation of Axin has been implicated in various cancers and developmental disorders, making it a significant focus of research in molecular biology. Understanding Axin's role in cellular processes can provide valuable insights into disease mechanisms and potential therapeutic approaches. Axin research continues to reveal new aspects of cellular regulation and development. Recent studies have highlighted Axin's involvement in additional signaling cascades beyond the Wnt pathway. Investigating Axin functions has become increasingly important for understanding both normal development and disease progression. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific knowledge of Axin's role in cellular processes and disease mechanisms.

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Axin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Axin Antibody (2B11)

sc-293190mouse IgG2a κ643-740 (h)WB, IP, IF, IHC(P), ELISAh
11
(6)

Axin Antibody (AT1A4)

sc-517389mouse IgG2b κ546-752 (h)WB, IP, IF, ELISAh

new

(0)

Axin Antibody (G-3)

sc-518090mouse IgG1 κ336-360 (m)WB, IP, IF, ELISAm, r, h
1
(1)

Axin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Axin CRISPR/Cas9 KO Plasmid (h)

sc-401074hGene KnockoutGFP
1
(0)

Axin HDR Plasmid (h)

sc-401074-HDRhHomology Directed RepairPuromycin
1
(0)

Axin Double Nickase Plasmid (h)

sc-401074-NIChGene KnockoutPuromycin
1
(0)

Axin Double Nickase Plasmid (h2)

sc-401074-NIC-2hGene KnockoutPuromycin
1
(0)

Axin CRISPR/Cas9 KO Plasmid (m)

sc-419277mGene KnockoutGFP0
(0)

Axin HDR Plasmid (m)

sc-419277-HDRmHomology Directed RepairPuromycin0
(0)

Axin Double Nickase Plasmid (m)

sc-419277-NICmGene KnockoutPuromycin0
(0)

Axin Double Nickase Plasmid (m2)

sc-419277-NIC-2mGene KnockoutPuromycin0
(0)

Axin CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Axin CRISPR Activation Plasmid (h)

sc-401074-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Axin CRISPR Activation Plasmid (h2)

sc-401074-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Axin Lentiviral Activation Particles (h)

sc-401074-LAChGene ActivationPuro, Blast, Hygro
1
(0)

Axin Lentiviral Activation Particles (h2)

sc-401074-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

Axin CRISPR Activation Plasmid (m)

sc-419277-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Axin CRISPR Activation Plasmid (m2)

sc-419277-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Axin Lentiviral Activation Particles (m)

sc-419277-LACmGene ActivationPuro, Blast, Hygro0
(0)

Axin Lentiviral Activation Particles (m2)

sc-419277-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Axin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Axin siRNA (h)

sc-41449hGene SilencingN/A
5
(0)

Axin shRNA Plasmid (h)

sc-41449-SHhGene SilencingPuromycin
5
(0)

Axin shRNA (h) Lentiviral Particles

sc-41449-VhGene SilencingPuromycin
5
(0)

Axin siRNA (m)

sc-41450mGene SilencingN/A
4
(0)

Axin shRNA Plasmid (m)

sc-41450-SHmGene SilencingPuromycin
4
(0)

Axin shRNA (m) Lentiviral Particles

sc-41450-VmGene SilencingPuromycin
4
(0)