ArpM1 activators represent a specialized category of compounds designed to target and enhance the activity of the ArpM1 protein. ArpM1, or Actin-Related Protein M1, is a member of the actin-related protein (Arp) family, which plays a crucial role in cytoskeletal dynamics and cellular processes that involve actin filament remodeling. Actin is a fundamental protein involved in cell motility, structural support, and intracellular transport. ArpM1 is specifically associated with actin-related functions within cells. Activators of ArpM1 are designed to upregulate its biological activity or stability, potentially influencing its role in actin filament regulation and cytoskeletal dynamics. These activators may encompass a range of chemical structures, from small organic molecules to larger biomolecules, each selectively interacting with ArpM1 to modulate its function within cells.
Research into ArpM1 activators typically involves a multidisciplinary approach, combining techniques from cell biology, biochemistry, and structural biology to elucidate their effects on ArpM1 function and their impact on actin-related cellular processes. Scientists investigate the interaction between ArpM1 and its activators by examining changes in actin filament dynamics, cellular morphology, and cellular motility. Commonly used techniques include fluorescence microscopy to visualize actin filaments, co-immunoprecipitation to identify protein-protein interactions, and live-cell imaging to monitor cellular motility in real-time. Additionally, in vitro assays using purified ArpM1 protein can provide insights into its biochemical properties and its modulation by specific activators. Through these investigations, researchers aim to understand the precise mechanisms by which ArpM1 regulates actin filament dynamics, how its activity is controlled, and how modulation by specific activators can impact cellular processes that rely on the dynamic rearrangement of actin filaments, contributing to a deeper understanding of cytoskeletal biology and cell motility.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
As an HSP90 inhibitor, Geldanamycin could destabilize client proteins and alter signal transduction pathways, potentially influencing ACTRT3 expression. |