ArpM1 Activators
ArpM1 activators represent a specialized category of compounds designed to target and enhance the activity of the ArpM1 protein. ArpM1, or Actin-Related Protein M1, is a member of the actin-related protein (Arp) family, which plays a crucial role in cytoskeletal dynamics and cellular processes that involve actin filament remodeling. Actin is a fundamental protein involved in cell motility, structural support, and intracellular transport. ArpM1 is specifically associated with actin-related functions within cells. Activators of ArpM1 are designed to upregulate its biological activity or stability, potentially influencing its role in actin filament regulation and cytoskeletal dynamics. These activators may encompass a range of chemical structures, from small organic molecules to larger biomolecules, each selectively interacting with ArpM1 to modulate its function within cells.
Research into ArpM1 activators typically involves a multidisciplinary approach, combining techniques from cell biology, biochemistry, and structural biology to elucidate their effects on ArpM1 function and their impact on actin-related cellular processes. Scientists investigate the interaction between ArpM1 and its activators by examining changes in actin filament dynamics, cellular morphology, and cellular motility. Commonly used techniques include fluorescence microscopy to visualize actin filaments, co-immunoprecipitation to identify protein-protein interactions, and live-cell imaging to monitor cellular motility in real-time. Additionally, in vitro assays using purified ArpM1 protein can provide insights into its biochemical properties and its modulation by specific activators. Through these investigations, researchers aim to understand the precise mechanisms by which ArpM1 regulates actin filament dynamics, how its activity is controlled, and how modulation by specific activators can impact cellular processes that rely on the dynamic rearrangement of actin filaments, contributing to a deeper understanding of cytoskeletal biology and cell motility.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, regulates gene expression by activating nuclear receptors, which could affect ACTRT3 levels. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As an inhibitor of histone deacetylase, Trichostatin A can alter chromatin structure and thus potentially increase ACTRT3 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound is a DNA methyltransferase inhibitor, which can cause hypomethylation of genes and potentially upregulate ACTRT3 expression. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
As a cell-permeable cAMP analog, it can activate protein kinase A, potentially influencing ACTRT3 expression through cAMP response element-binding protein (CREB). | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C, which could lead to changes in transcriptional regulation, possibly affecting ACTRT3 expression. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Sodium valproate is known to have histone deacetylase inhibitory activity, which could potentially upregulate gene expression, including that of ACTRT3. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium impacts GSK-3 signaling and through this pathway could hypothetically influence ACTRT3 transcription. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As a tyrosine kinase inhibitor, Genistein might modify signaling pathways and alter gene expression profile, potentially including ACTRT3. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
By affecting transcription factors such as NRF2, sulforaphane may alter gene expression patterns with possible effects on ACTRT3. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea can influence the cell cycle and DNA repair mechanisms, which might impact gene expression, including that of ACTRT3. | ||||||