Date published: 2025-12-18

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AR Inhibitors

Santa Cruz Biotechnology now offers a broad range of AR Inhibitors for use in various applications. AR inhibitors, or Androgen Receptor inhibitors, are a critical category of chemicals widely utilized in scientific research to investigate the mechanisms of androgen signaling, which is fundamental to numerous physiological processes, including development, metabolism, and reproductive functions. The androgen receptor (AR) is a nuclear receptor that, upon binding with androgens like testosterone, regulates the expression of target genes involved in cellular growth, differentiation, and homeostasis. By using AR inhibitors, researchers can effectively block the activity of the androgen receptor, enabling detailed studies of the pathways and gene networks controlled by androgens. This inhibition is particularly valuable for understanding the role of androgen signaling in various biological contexts, including the regulation of muscle and bone metabolism, hair growth, and sexual differentiation. AR inhibitors are also essential tools for exploring the complex interactions between androgen signaling and other hormonal pathways, helping to study how these pathways are integrated within cellular and systemic functions. In addition, these inhibitors are used in studies focused on gene expression analysis, where the inhibition of AR activity can reveal the downstream effects of androgen signaling on specific cellular processes. The availability of a diverse range of AR inhibitors allows researchers to fine-tune their experimental approaches to dissect the nuanced roles of the androgen receptor in health and disease, providing crucial insights into the molecular mechanisms underlying androgen-related biological effects. View detailed information on our available AR Inhibitors by clicking on the product name.

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Items 21 to 30 of 59 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,3-Dimethyl-8-phenylxanthine

961-45-5sc-253981
50 mg
$148.00
(0)

1,3-Dimethyl-8-phenylxanthine showcases remarkable structural versatility, characterized by its ability to engage in π-π stacking interactions due to its aromatic phenyl group. This feature enhances its stability in nonpolar environments. The compound's unique xanthine backbone facilitates specific hydrogen bonding patterns, influencing its solubility and reactivity. Additionally, its electron-donating methyl groups can modulate electronic properties, affecting interaction kinetics with various substrates.

Apalutamide

956104-40-8sc-507442
5 mg
$290.00
(0)

ARN-509 is another androgen receptor antagonist under investigation for advanced prostate cancer research.

Doxepin hydrochloride

1229-29-4sc-203930
1 g
$51.00
(1)

Doxepin hydrochloride exhibits intriguing properties as an aromatic compound, primarily due to its dual amine and ether functionalities. The presence of a tertiary amine allows for strong dipole-dipole interactions, enhancing solubility in polar solvents. Its unique tricyclic structure promotes conformational flexibility, which can influence molecular recognition processes. Furthermore, the compound's ability to form stable complexes through hydrogen bonding contributes to its reactivity in various chemical environments.

(R)-(+)-Propranolol hydrochloride

5051-22-9sc-203678
sc-203678A
100 mg
1 g
$70.00
$332.00
(0)

(R)-(+)-Propranolol hydrochloride is characterized by its chiral structure, which influences its interaction with biological receptors. The compound features a naphthalene ring that enhances π-π stacking interactions, promoting stability in complex formations. Its secondary amine group facilitates hydrogen bonding, allowing for specific molecular recognition. Additionally, the compound's hydrophilic hydrochloride moiety increases solubility in aqueous environments, affecting its diffusion and reactivity in various chemical contexts.

Fenspiride Hydrochloride

5053-08-7sc-207684
10 mg
$185.00
(0)

Fenspiride Hydrochloride exhibits unique properties due to its dual action as an anti-inflammatory and bronchodilator. Its structure allows for specific interactions with neurotransmitter receptors, influencing signal transduction pathways. The presence of a tertiary amine enhances its ability to form ionic bonds, while the hydrochloride salt form increases its solubility, facilitating rapid distribution in polar environments. This compound's distinct electronic configuration also contributes to its reactivity in various chemical processes.

Clomipramine hydrochloride

17321-77-6sc-203898
1 g
$37.00
2
(1)

Clomipramine hydrochloride is characterized by its complex molecular interactions, particularly its ability to form hydrogen bonds due to the presence of a secondary amine. This facilitates unique conformational changes that influence its reactivity. The hydrochloride form enhances its solubility in aqueous environments, promoting effective diffusion. Additionally, its aromatic structure allows for π-π stacking interactions, which can affect its stability and reactivity in various chemical contexts.

ent-Levobunolol, Hydrochloride

27867-05-6sc-211411
100 mg
$300.00
(0)

Ent-Levobunolol hydrochloride exhibits intriguing molecular dynamics, particularly through its chiral center, which influences stereoselectivity in reactions. The presence of a hydroxyl group enables strong hydrogen bonding, enhancing its solubility and reactivity in polar solvents. Its unique spatial arrangement allows for specific interactions with biological macromolecules, potentially affecting its kinetic behavior in various environments. The compound's aromatic moiety contributes to its electronic properties, facilitating resonance stabilization.

Propafenone Hydrochloride

34183-22-7sc-204863
sc-204863A
sc-204863B
sc-204863C
1 g
5 g
25 g
100 g
$21.00
$65.00
$194.00
$491.00
(1)

Propafenone Hydrochloride showcases distinctive electronic characteristics due to its aromatic structure, which enhances π-π stacking interactions. The compound's unique aliphatic chain facilitates hydrophobic interactions, influencing its solubility profile in non-polar environments. Additionally, the presence of a tertiary amine allows for potential protonation, altering its reactivity and interaction dynamics in various chemical contexts. Its stereochemistry may also play a role in influencing reaction pathways and kinetics.

Acebutolol Hydrochloride

34381-68-5sc-217555
10 g
$300.00
(1)

Acebutolol Hydrochloride exhibits intriguing electrostatic properties stemming from its polar functional groups, which promote dipole-dipole interactions. The compound's unique cyclic structure contributes to its conformational flexibility, allowing for diverse molecular orientations that can affect solubility in various solvents. Furthermore, the presence of a secondary amine enhances its ability to engage in hydrogen bonding, potentially influencing its reactivity and interaction with other chemical species.

Levobunolol, Hydrochloride

27912-14-7sc-211734
sc-211734A
100 mg
250 mg
$320.00
$726.00
(1)

Levobunolol Hydrochloride features a distinctive chiral center that imparts stereochemical diversity, influencing its interaction with biological targets. Its aromatic ring system enhances π-π stacking interactions, which can affect its solubility and stability in different environments. The compound's ability to form stable complexes through coordination with metal ions may also play a role in its reactivity, while its hydrophilic and lipophilic balance allows for varied solvation dynamics.