1,3-Dimethyl-8-phenylxanthine (CAS 961-45-5)

1,3-Dimethyl-8-phenylxanthine is a xanthine derivative widely utilized in scientific research. As a structural analog of theophylline, it serves as useful for investigating the effects of xanthines on various biochemical and physiological systems. Numerous experiments have employed 1,3-Dimethyl-8-phenylxanthine to explore its impact on the cardiovascular system, respiratory system, and central nervous system. Moreover, it has been an essential component in studying how caffeine and other xanthines influence the body. Delving further into its applications, 1,3-Dimethyl-8-phenylxanthinehas been instrumental in researching the effects of xanthines on fatty acid and glucose metabolism, as well as their influence on muscle contraction and relaxation. Additionally, it has played a pivotal role in understanding the regulation of calcium and potassium channels by xanthines. Mechanistically, 1,3-Dimethyl-8-phenylxanthine acts as an adenosine receptor antagonist, effectively obstructing adenosine′s action on its target receptors. This inhibition results in the blockade of adenosine-mediated processes, including the modulation of neuronal firing and smooth muscle relaxation. Furthermore, 1,3-Dimethyl-8-phenylxanthine functions as a phosphodiesterase inhibitor, leading to increased levels of cAMP in the body. Elevated cAMP levels contribute to an increase in calcium levels, which can, in turn, impact muscle contraction and relaxation.