Date published: 2026-4-13

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APPL2 Antibodies

Santa Cruz Biotechnology delivers a wide array of APPL2 monoclonal antibodies for research focused on understanding APPL2 protein functions. APPL2 monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). APPL2, or adaptor protein containing PH domain, PTB domain, and leucine zipper, plays a crucial role in cellular signaling and endocytosis. APPL2 actively participates in the regulation of insulin signaling pathways. Research has shown that APPL2 significantly influences cell growth and differentiation processes. Current studies indicate that APPL2 may have important implications in metabolic disorders and cancer development. Understanding APPL2 functions continues to reveal new insights into cellular mechanisms. Investigating APPL2 opens new possibilities for therapeutic interventions in various diseases. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of APPL2's role in human health and disease.

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APPL2 Antibodies

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APPL2 Antibody (F-2)

sc-398859mouse IgG2a κ31-54 (h)WB, IP, IF, ELISAm, r, h
1
(3)

APPL2 Antibody (B-12)

sc-398860mouse IgG2b κ31-54 (h)WB, IP, IF, ELISAm, r, h

new

(2)

APPL2 Antibody (E-1)

sc-271084mouse IgG1 κ605-664 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

APPL2 CRISPR Knockout, HDR and Double Nickase Plasmids

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APPL2 CRISPR/Cas9 KO Plasmid (h)

sc-402991hGene KnockoutGFP0
(0)

APPL2 HDR Plasmid (h)

sc-402991-HDRhHomology Directed RepairPuromycin0
(0)

APPL2 CRISPR/Cas9 KO Plasmid (m)

sc-432068mGene KnockoutGFP0
(0)

APPL2 HDR Plasmid (m)

sc-432068-HDRmHomology Directed RepairPuromycin0
(0)

APPL2 CRISPR Activation Products

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APPL2 CRISPR Activation Plasmid (m2)

sc-432068-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

APPL2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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APPL2 siRNA (h)

sc-61982hGene SilencingN/A0
(0)

APPL2 shRNA Plasmid (h)

sc-61982-SHhGene SilencingPuromycin0
(0)

APPL2 shRNA (h) Lentiviral Particles

sc-61982-VhGene SilencingPuromycin0
(0)

APPL2 siRNA (m)

sc-61983mGene SilencingN/A0
(0)

APPL2 shRNA Plasmid (m)

sc-61983-SHmGene SilencingPuromycin0
(0)

APPL2 shRNA (m) Lentiviral Particles

sc-61983-VmGene SilencingPuromycin0
(0)