Chemicals associated with the indirect activation of ANKRD25 typically interact with a diverse range of signaling pathways, consequently influencing the protein's modulation. Agents like Retinoic Acid, which operates via retinoic acid receptors, exert influence on gene transcription processes. Such modulation of transcriptional landscapes can impact proteins like ANKRD25 that are speculated to play roles in these cascades. Similarly, chemicals like AICAR and Metformin, renowned AMPK activators, elucidate the interconnection between cellular energy dynamics and proteins like ANKRD25. Activation of AMPK can trigger a cascade of events, leading to the indirect modulation of ANKRD25.
Another profound domain influencing ANKRD25 activation revolves around intracellular cAMP levels. Dibutyryl-cAMP, a cell-permeable analog, and Rolipram, a PDE4, both elevate intracellular cAMP levels, a key secondary messenger. As cAMP modulates a multitude of signaling cascades, its increase can steer the pathways in which ANKRD25 operates, fostering its indirect modulation. In a similar vein, PMA, a potent PKC activator, underscores the relevance of protein kinases in cellular signaling. Enhancement of PKC activity can ripple through to downstream effectors and pathways, indirectly modulating ANKRD25. Moreover, agents such as SAG and DAPT, which modulate the Hedgehog and Notch signaling pathways respectively, highlight the intricate network of signaling events that proteins like ANKRD25 are possibly entrenched in. Chemicals such as these, even in the absence of direct binding or interaction with ANKRD25, shed light on the versatile means by which ANKRD25's function can be swayed, predominantly via the indirect activation of associated signaling pathways.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of Vitamin A that can modulate gene expression via retinoic acid receptors. By influencing gene transcription processes where ANKRD25 may play a role, it indirectly supports the modulation of ANKRD25. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
An AMPK activator, which is involved in cellular energy regulation. By stimulating AMPK, AICAR can activate downstream pathways where ANKRD25 may be involved, indirectly leading to its modulation. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
An AMPK activator. Similar to AICAR, by boosting AMPK activity, Metformin can indirectly modulate processes where ANKRD25 participates, leading to its potential activation. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
A cell-permeable cAMP analog. By raising intracellular cAMP levels, it can influence various signaling cascades that may intersect with pathways in which ANKRD25 operates, facilitating its indirect modulation. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
A PDE4 inhibitor that elevates intracellular cAMP levels. Through this mechanism, it may indirectly modulate signaling processes where ANKRD25 plays a role. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
A protein kinase C (PKC) activator. By enhancing PKC activity, it may influence downstream effectors and pathways that can modulate ANKRD25 indirectly. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
A broad-spectrum phosphodiesterase (PDE) inhibitor. By elevating cAMP and cGMP levels, IBMX can activate several cascades, potentially leading to the indirect modulation of ANKRD25. | ||||||
Smoothened Agonist, HCl | 364590-63-6 | sc-202814 sc-202814A | 1 mg 5 mg | $206.00 $510.00 | 31 | |
An activator of the Hedgehog signaling pathway. By boosting this pathway, SAG can affect downstream proteins and processes that could indirectly support the role of ANKRD25. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
An inhibitor of γ-secretase, impacting the Notch signaling pathway. As the Notch pathway can intersect with other signaling events where ANKRD25 might be implicated, DAPT can modulate ANKRD25 indirectly. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $57.00 $184.00 $867.00 | 10 | |
An inhibitor of GSK3β, affecting the Wnt/β-catenin pathway. Even though Wnt proteins are excluded, by acting on GSK3β, BIO can modulate the downstream events where ANKRD25 may play a role, leading to its indirect modulation. |