Date published: 2025-10-10

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ANKRD25 Activators

Chemicals associated with the indirect activation of ANKRD25 typically interact with a diverse range of signaling pathways, consequently influencing the protein's modulation. Agents like Retinoic Acid, which operates via retinoic acid receptors, exert influence on gene transcription processes. Such modulation of transcriptional landscapes can impact proteins like ANKRD25 that are speculated to play roles in these cascades. Similarly, chemicals like AICAR and Metformin, renowned AMPK activators, elucidate the interconnection between cellular energy dynamics and proteins like ANKRD25. Activation of AMPK can trigger a cascade of events, leading to the indirect modulation of ANKRD25.

Another profound domain influencing ANKRD25 activation revolves around intracellular cAMP levels. Dibutyryl-cAMP, a cell-permeable analog, and Rolipram, a PDE4, both elevate intracellular cAMP levels, a key secondary messenger. As cAMP modulates a multitude of signaling cascades, its increase can steer the pathways in which ANKRD25 operates, fostering its indirect modulation. In a similar vein, PMA, a potent PKC activator, underscores the relevance of protein kinases in cellular signaling. Enhancement of PKC activity can ripple through to downstream effectors and pathways, indirectly modulating ANKRD25. Moreover, agents such as SAG and DAPT, which modulate the Hedgehog and Notch signaling pathways respectively, highlight the intricate network of signaling events that proteins like ANKRD25 are possibly entrenched in. Chemicals such as these, even in the absence of direct binding or interaction with ANKRD25, shed light on the versatile means by which ANKRD25's function can be swayed, predominantly via the indirect activation of associated signaling pathways.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

A metabolite of Vitamin A that can modulate gene expression via retinoic acid receptors. By influencing gene transcription processes where ANKRD25 may play a role, it indirectly supports the modulation of ANKRD25.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$60.00
$270.00
$350.00
48
(2)

An AMPK activator, which is involved in cellular energy regulation. By stimulating AMPK, AICAR can activate downstream pathways where ANKRD25 may be involved, indirectly leading to its modulation.

Metformin

657-24-9sc-507370
10 mg
$77.00
2
(0)

An AMPK activator. Similar to AICAR, by boosting AMPK activity, Metformin can indirectly modulate processes where ANKRD25 participates, leading to its potential activation.

Dibutyryl-cAMP

16980-89-5sc-201567
sc-201567A
sc-201567B
sc-201567C
20 mg
100 mg
500 mg
10 g
$45.00
$130.00
$480.00
$4450.00
74
(7)

A cell-permeable cAMP analog. By raising intracellular cAMP levels, it can influence various signaling cascades that may intersect with pathways in which ANKRD25 operates, facilitating its indirect modulation.

Rolipram

61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$75.00
$212.00
18
(1)

A PDE4 inhibitor that elevates intracellular cAMP levels. Through this mechanism, it may indirectly modulate signaling processes where ANKRD25 plays a role.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

A protein kinase C (PKC) activator. By enhancing PKC activity, it may influence downstream effectors and pathways that can modulate ANKRD25 indirectly.

IBMX

28822-58-4sc-201188
sc-201188B
sc-201188A
200 mg
500 mg
1 g
$159.00
$315.00
$598.00
34
(1)

A broad-spectrum phosphodiesterase (PDE) inhibitor. By elevating cAMP and cGMP levels, IBMX can activate several cascades, potentially leading to the indirect modulation of ANKRD25.

Smoothened Agonist, HCl

364590-63-6sc-202814
sc-202814A
1 mg
5 mg
$206.00
$510.00
31
(1)

An activator of the Hedgehog signaling pathway. By boosting this pathway, SAG can affect downstream proteins and processes that could indirectly support the role of ANKRD25.

DAPT

208255-80-5sc-201315
sc-201315A
sc-201315B
sc-201315C
5 mg
25 mg
100 mg
1 g
$99.00
$335.00
$836.00
$2099.00
47
(3)

An inhibitor of γ-secretase, impacting the Notch signaling pathway. As the Notch pathway can intersect with other signaling events where ANKRD25 might be implicated, DAPT can modulate ANKRD25 indirectly.

GSK-3 Inhibitor IX

667463-62-9sc-202634
sc-202634A
sc-202634B
1 mg
10 mg
50 mg
$57.00
$184.00
$867.00
10
(1)

An inhibitor of GSK3β, affecting the Wnt/β-catenin pathway. Even though Wnt proteins are excluded, by acting on GSK3β, BIO can modulate the downstream events where ANKRD25 may play a role, leading to its indirect modulation.