Date published: 2026-1-9

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alpha-gal A Substrates

Santa Cruz Biotechnology now offers a broad range of alpha-gal A Substrates for use in various applications. Alpha-gal A Substrates are essential tools in scientific research, particularly for studying the activity of the enzyme alpha-galactosidase A (alpha-gal A), which is crucial for the degradation of glycolipids such as globotriaosylceramide (Gb3) in lysosomes. This enzyme's function is vital for cellular homeostasis, as it prevents the accumulation of harmful glycolipids that can lead to cellular dysfunction. By using specific alpha-gal A Substrates, researchers can monitor and measure the enzyme's activity in various biological systems, providing insights into the molecular mechanisms of glycolipid metabolism. These substrates are particularly valuable in studies aimed at understanding the biochemical pathways involved in lysosomal storage disorders, where a deficiency in alpha-gal A activity can result in the accumulation of undegraded substrates within cells. In the scientific community, alpha-gal A Substrates are widely used in enzyme assays, cell culture experiments, and other biochemical analyses to explore how alterations in alpha-gal A activity affect cellular functions and contribute to disease processes. Researchers employ these substrates to investigate the role of alpha-gal A in normal physiology and to study the consequences of its dysfunction in various experimental models. The availability of high-quality alpha-gal A Substrates is crucial for advancing research in fields such as biochemistry, cell biology, and molecular genetics, offering precise tools to study the enzyme's role in health and disease. View detailed information on our available alpha-gal A Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

4-Nitrophenyl α-D-galactopyranoside

7493-95-0sc-220978
sc-220978A
100 mg
500 mg
$37.00
$97.00
1
(0)

4-Nitrophenyl α-D-galactopyranoside acts as an alpha-gal A by engaging in specific glycosidic bond cleavage, driven by its nitrophenyl group, which enhances electrophilicity. This compound exhibits notable reactivity due to its ability to stabilize transition states during enzymatic hydrolysis. Its structural features promote selective interactions with glycosidases, influencing reaction rates and pathways, while its solubility in various solvents allows for versatile experimental applications.

4-Methylumbelliferyl-α- D-galactopyranoside

38597-12-5sc-280454
sc-280454A
sc-280454B
sc-280454C
sc-280454D
50 mg
100 mg
250 mg
500 mg
1 g
$130.00
$193.00
$312.00
$525.00
$838.00
8
(1)

4-Methylumbelliferyl-α-D-galactopyranoside serves as a substrate for alpha-galactosidase, showcasing unique fluorescence properties upon enzymatic cleavage. The presence of the methylumbelliferyl moiety enhances its sensitivity to enzymatic activity, allowing for real-time monitoring of hydrolysis. This compound's structural configuration facilitates specific binding interactions with glycosidases, influencing catalytic efficiency and reaction dynamics, while its solubility profile supports diverse analytical techniques.

6-Bromo-2-naphthyl-α-D-galactopyranoside

25997-59-5sc-221088
100 mg
$360.00
(0)

6-Bromo-2-naphthyl-α-D-galactopyranoside acts as a selective substrate for alpha-galactosidase, characterized by its unique naphthyl group that enhances hydrophobic interactions with the enzyme's active site. This compound exhibits distinct reaction kinetics, with a notable increase in turnover rate due to its sterically favorable structure. Its solubility in organic solvents allows for versatile applications in biochemical assays, while the bromine substituent may influence electronic properties, affecting reactivity and stability.