Date published: 2026-5-18

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α-actinin-2 Activators

α-actinin-2 Activators constitute a specific group of chemical compounds known for their capacity to modulate the activity of alpha-actinin-2. This chemical class functions by interacting with and enhancing the signaling pathways associated with alpha-actinin-2, a cytoskeletal protein that plays a pivotal role in mediating cellular adhesion, cytoskeletal organization, and mechanical stability. Alpha-actinin-2 is recognized for its involvement in various cellular processes, including cell motility, cell-cell interactions, and maintenance of tissue integrity.

α-actinin-2 Activators exert their influence through specific molecular interactions that may amplify the downstream effects of alpha-actinin-2-mediated signaling, contributing to the fine-tuning of cell adhesion, cytoskeletal dynamics, and cellular responses to mechanical forces. The intricate mechanisms through which α-actinin-2 Activators impact alpha-actinin-2-related pathways remain a focus of ongoing scientific exploration, offering insights into the complex interplay between cell adhesion, biomechanics, and cellular behaviors. The specific ways in which this chemical class engages with alpha-actinin-2 underscore its significance in unraveling the intricacies of cellular structure and function, enhancing our understanding across various scientific domains.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$28.00
$38.00
5
(0)

Activation of β-adrenergic receptors by compounds like isoproterenol can induce α-actinin-2 expression, especially in cardiac muscle cells.

Cobalt(II) chloride

7646-79-9sc-252623
sc-252623A
5 g
100 g
$64.00
$176.00
7
(1)

Cobalt chloride induces HIF-1α stabilization, mimicking hypoxic conditions and potentially affecting α-actinin-2 expression.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$96.00
$264.00
2
(2)

Ionomycin elevates intracellular calcium levels, influencing calcium-dependent signaling pathways that could impact α-actinin-2 expression.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Glucocorticoid hormones can influence muscle gene expression, including α-actinin-2, in various contexts.

Angiotensin II, Human

4474-91-3sc-363643
sc-363643A
sc-363643B
sc-363643C
1 mg
5 mg
25 mg
100 mg
$51.00
$100.00
$310.00
$690.00
3
(1)

Angiotensin II can influence cardiac gene expression, including α-actinin-2, in the context of heart disease.