AI-BP Activators
AI-BP activators comprise a set of chemical compounds that indirectly enhance the functional activity of AI-BP through various signaling pathways and metabolic processes. Resveratrol and NAD+ primarily act by activating the SIRT1 pathway and providing essential cofactors for sirtuin enzymes, which are intimately involved in mitochondrial function, a key area of AI-BP activity. Similarly, the PPARγ agonist Rosiglitazone and AMPK activators like AICAR and Berberine work by modulating lipid metabolism and energy homeostasis. Rosiglitazone's role in adipogenesis and fatty acid storage, along with the influence of AICAR and Berberine on mitochondrial biogenesis and lipid metabolism, all serve to indirectly enhance the activity of AI-BP in these pathways. L-Carnitine and Coenzyme Q10 further support this enhancement by optimizing fatty acid transport into mitochondria and ensuring efficient ATP synthesis, respectively.
Ob (hBA-147), through its regulatory role in energy balance, indirectly influences AI-BP activity by affecting energy expenditure and mitochondrial dynamics. Metformin, alsoan activator of AMPK, similarly promotes AI-BP activity by bolstering catabolic processes that produce ATP, pivotal for AI-BP's role in energy management. Alpha-lipoic acid, with its mitochondrial bioenergetic support, and Nicotinamide riboside, as a NAD+ precursor, both enhance sirtuin-associated deacetylation functions, thus indirectly augmenting AI-BP's functionality in energy metabolism. Lastly, Curcumin's activation of AMPK leads to metabolic adjustments that support AI-BP's involvement in mitochondrial function, rounding out the spectrum of AI-BP activators that, through their targeted biochemical actions, collectively enhance the protein's role in cellular energy processes without directly altering its expression or activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates the SIRT1 pathway, which deacetylates proteins that contribute to cellular regulation. SIRT1 activation enhances the activity of AI-BP by improving mitochondrial function and energy production. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+ is a coenzyme found in all living cells and is essential for energy production. Increased NAD+ levels can enhance the deacetylation activity of AI-BP by providing the necessary cofactor for sirtuin enzymes, thus influencing metabolic and mitochondrial functions. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone, a PPARγ agonist, enhances adipogenesis and fatty acid storage. Activation of PPARγ indirectly enhances AI-BP activity by promoting lipid metabolism and transport, processes in which AI-BP is fundamentally involved. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR is an activator of AMP-activated protein kinase (AMPK), a central regulator of cellular energy homeostasis. Through AMPK activation, AICAR can indirectly increase AI-BP activity by enhancing fatty acid oxidation and mitochondrial biogenesis where AI-BP has a functional role. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $34.00 $79.00 $179.00 | 3 | |
L-Carnitine is essential for the transport of fatty acids into mitochondria for β-oxidation. By facilitating fatty acid transport, L-Carnitine indirectly enhances AI-BP function in mitochondrial fatty acid oxidation pathways. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Coenzyme Q10 is involved in the electron transport chain and is essential for ATP synthesis. By supporting mitochondrial function, it indirectly enhances AI-BP activity, which is associated with effective energy production. | ||||||
Ob (hBA-147) | sc-4912 | 1000 µg | $258.00 | 1 | ||
Ob (hBA-147) is a hormone that regulates energy balance. By signaling through its receptors, Ob (hBA-147) can indirectly influence AI-BP activity by modulating energy expenditure and mitochondrial function where AI-BP is implicated. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine activates AMPK and modulates metabolic function. Through AMPK activation, Berberine can enhance AI-BP activity by influencing mitochondrial function and promoting lipid metabolism. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Alpha-lipoic acid is an antioxidant that helps regenerate other antioxidants and is involved in mitochondrial bioenergetics. It indirectly enhances AI-BP activity by improving mitochondrial function and influencing fatty acid metabolism. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside is a precursor of NAD+ and thus can enhance sirtuin activity, including the deacetylation functions associated with AI-BP, leading to improved mitochondrial function and energy metabolism. | ||||||