Date published: 2026-4-24

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AE2 Activators

The chemical class of AE2 activators comprises a diverse set of compounds that can modulate the activity of AE2, a critical player in cellular processes. Amphotericin B interacts with membrane components, influencing AE2 by altering the cellular environment. Omeprazole, a proton pump inhibitor, indirectly modulates AE2 by affecting intracellular acidity, impacting its sensitivity to pH changes. Forskolin activates adenylate cyclase, leading to increased cAMP levels, influencing AE2 through downstream cAMP-mediated signaling pathways. Nifedipine, a calcium channel blocker, indirectly impacts AE2 by modulating intracellular calcium levels and associated signaling processes. 8-Br-cAMP, a cAMP analog, directly influences cellular processes associated with cAMP-mediated signaling, affecting AE2 activity through altered intracellular signaling cascades. Butyrate, a short-chain fatty acid, and Diclofenac, an NSAID, can indirectly modulate AE2 by influencing cellular metabolism, inflammatory responses, and stress pathways.

Tauroursodeoxycholic acid (TUDCA), a bile acid derivative, indirectly influences AE2 by modulating cellular stress responses. A23187, a calcium ionophore, directly impacts intracellular calcium levels, affecting AE2 activity through alterations in calcium-dependent regulatory mechanisms. Cisplatin indirectly modulates AE2 by influencing cellular stress responses. Sodium Butyrate, a short-chain fatty acid, similar to Butyrate, can modulate AE2 by affecting cellular metabolism and epigenetic regulation. Carbachol, a cholinergic agonist, indirectly influences AE2 by activating muscarinic receptors and initiating downstream signaling cascades. This diverse array of AE2 activators offers researchers valuable tools to explore the intricate regulation of AE2 in various cellular contexts, providing insights into its role in health and disease.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Amphotericin B

1397-89-3sc-202462
sc-202462A
sc-202462B
100 mg
500 mg
1 g
$70.00
$142.00
$223.00
10
(1)

Amphotericin B is an antifungal agent in research that directly interacts with membrane components, potentially influencing the cellular environment surrounding AE2. Changes in the membrane composition may impact AE2 activity indirectly.

Omeprazole

73590-58-6sc-202265
50 mg
$67.00
4
(1)

Omeprazole, a proton pump inhibitor, indirectly influences AE2 by modulating the acidity of intracellular compartments. As AE2 is sensitive to pH changes, alterations in cellular acidity can affect AE2 activity, making Omeprazole a potential indirect modulator.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, leading to increased cAMP levels. Elevated cAMP levels can modulate cellular processes, potentially impacting AE2 indirectly through downstream signaling pathways associated with cAMP-mediated regulation.

Nifedipine

21829-25-4sc-3589
sc-3589A
1 g
5 g
$59.00
$173.00
15
(1)

Nifedipine is a calcium channel blocker that can indirectly influence AE2. By modulating intracellular calcium levels, Nifedipine may impact cellular processes associated with calcium signaling, potentially influencing AE2 activity in response to altered calcium dynamics.

8-Bromo-cAMP

76939-46-3sc-201564
sc-201564A
10 mg
50 mg
$126.00
$328.00
30
(1)

8-Br-cAMP is a cell-permeable analog of cAMP, directly influencing cellular processes associated with cAMP-mediated signaling. Its impact on downstream pathways may indirectly affect AE2 activity through altered intracellular signaling cascades.

Butyric acid

107-92-6sc-214640
sc-214640A
1 kg
10 kg
$64.00
$177.00
(0)

Butyrate is a short-chain fatty acid that can influence AE2 indirectly through its role in cellular metabolism and epigenetic regulation. Changes in cellular metabolism and epigenetic modifications may impact the regulatory mechanisms of AE2, making Butyrate a potential indirect modulator.

Diclofenac acid

15307-86-5sc-357332
sc-357332A
5 g
25 g
$109.00
$298.00
5
(1)

Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), can indirectly impact AE2 activity by modulating inflammatory responses. Inflammatory mediators may influence the regulatory pathways associated with AE2, making Diclofenac a potential indirect modulator of AE2.

Tauroursodeoxycholic Acid, Sodium Salt

14605-22-2sc-281165
1 g
$644.00
5
(1)

TUDCA is a bile acid derivative that can indirectly influence AE2 by modulating cellular stress responses. TUDCA's impact on cellular stress pathways may indirectly affect the regulatory mechanisms of AE2, making it a potential indirect modulator.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

A23187 is a calcium ionophore that can directly influence intracellular calcium levels. Changes in calcium dynamics may impact cellular processes associated with calcium signaling, potentially affecting AE2 activity directly through alterations in calcium-dependent regulatory mechanisms.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$138.00
$380.00
101
(4)

Cisplatin is a chemotherapeutic agent that can indirectly influence AE2 by modulating cellular stress responses. Its impact on stress pathways may indirectly affect the regulatory mechanisms of AE2, making Cisplatin a potential indirect modulator.