The class of chemicals known as ADCK4 activators consists of diverse compounds that can either directly influence the activity of the ADCK4 (COQ8B) protein or indirectly affect its functionality by modulating pathways or cellular processes associated with it. Notably, ADCK4 plays a pivotal role in the biosynthesis of coenzyme Q10 (CoQ10), a key molecule in the mitochondrial electron transport chain responsible for ATP production.
Among the activators, Pyrroloquinoline quinone, Lipoic acid, and MitoQ stand out for their direct influence on mitochondrial health and function. They enhance the overall mitochondrial environment, which can in turn support the activity of ADCK4. Ubiquinol, the reduced form of CoQ10, along with its synthetic analogue Idebenone, can upregulate ADCK4 activity, ensuring a consistent supply of CoQ10 to meet cellular demands. Additionally, cofactors such as FAD and NADH, essential for redox reactions and energy production in mitochondria, have a pivotal role in cellular processes that can activate or modulate ADCK4's function. Furthermore, compounds like N-acetyl cysteine (NAC) and Taurine emphasize their roles in antioxidation and ion flux regulation in mitochondria, respectively, showcasing the complex interplay of factors that can impact ADCK4's activity in the cell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
A redox cofactor that can indirectly activate ADCK4 by enhancing mitochondrial function and CoQ10 biosynthesis. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Functions as an antioxidant, potentially influencing mitochondrial pathways linked with ADCK4 activation. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
Involved in methylation processes that can modulate mitochondrial pathways, possibly impacting ADCK4. | ||||||
Mecobalamin | 13422-55-4 | sc-211781 | 10 mg | $300.00 | ||
A form of vitamin B12 that can support mitochondrial health, indirectly influencing ADCK4 function. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
Specifically targets mitochondria and can influence CoQ10-related processes, indirectly affecting ADCK4. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
An antioxidant that can support mitochondrial health, thus indirectly influencing ADCK4 activity. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $47.00 $100.00 | 1 | |
An amino acid that aids in the regulation of ion flux in mitochondria, potentially influencing ADCK4. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Has properties that promote mitochondrial function and can indirectly influence the activity of ADCK4. | ||||||