Date published: 2025-9-20

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 51 to 60 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

4-Propylbenzoyl chloride

52710-27-7sc-262147
sc-262147A
1 g
5 g
$36.00
$115.00
(0)

4-Propylbenzoyl chloride is a potent acid halide characterized by its strong electrophilic nature, primarily due to the presence of the benzoyl moiety. This compound readily participates in acylation reactions, where its propyl group can influence steric hindrance, affecting reaction rates and selectivity. The unique interactions between the carbonyl and halide functionalities enhance its reactivity, making it a key player in diverse synthetic transformations. Additionally, its behavior in different solvents can significantly impact the reaction kinetics, allowing for tailored synthetic strategies.

(−)-1-(9-Fluorenyl)ethyl chloroformate solution

154479-90-0sc-222600
1 ml
$271.00
(0)

(-)-1-(9-Fluorenyl)ethyl chloroformate solution exhibits remarkable reactivity as an acid halide, driven by its unique fluorene structure that enhances electrophilicity. This compound engages in acylation processes, where the bulky fluorene group introduces significant steric effects, influencing both the rate and selectivity of reactions. Its ability to form stable intermediates with nucleophiles is notable, and solvent interactions can further modulate its reactivity, providing versatility in synthetic applications.

Dichloroacetyl chloride

79-36-7sc-239701
sc-239701A
5 g
100 g
$31.00
$82.00
(0)

Dichloroacetyl chloride is a highly reactive acid halide characterized by its dual chlorine substituents, which enhance its electrophilic nature. This compound readily participates in acylation reactions, where the presence of two electronegative chlorine atoms facilitates the formation of reactive intermediates. Its strong tendency to undergo nucleophilic attack leads to rapid reaction kinetics, while its polar nature influences solubility and reactivity in various solvents, making it a versatile reagent in organic synthesis.

Dimethylcarbamyl chloride

79-44-7sc-239788
sc-239788A
5 g
100 g
$31.00
$32.00
(0)

Dimethylcarbamyl chloride is a potent acid halide known for its unique reactivity profile, primarily due to the presence of the dimethylcarbamyl group. This structure enhances its electrophilic character, allowing it to engage in acylation and amidation reactions with remarkable efficiency. The compound's ability to form stable intermediates during nucleophilic attacks is notable, and its polar characteristics contribute to its solubility in various organic solvents, facilitating diverse synthetic pathways.

Diphenylcarbamoyl chloride

83-01-2sc-239803
25 g
$50.00
(0)

Diphenylcarbamoyl chloride is a distinctive acid halide characterized by its dual phenyl groups, which significantly influence its reactivity. This compound exhibits a strong electrophilic nature, making it highly susceptible to nucleophilic attack. The steric bulk of the phenyl groups can modulate reaction kinetics, often leading to selective acylation processes. Additionally, its polar nature enhances solubility in organic solvents, promoting versatile synthetic applications and facilitating the formation of reactive intermediates.

Diethylcarbamoyl chloride

88-10-8sc-239745
100 g
$258.00
(0)

Diethylcarbamoyl chloride is a notable acid halide distinguished by its diethylamino group, which enhances its electrophilicity and reactivity towards nucleophiles. The presence of the ethyl groups introduces steric hindrance, influencing the selectivity of acylation reactions. Its ability to form stable intermediates with amines and alcohols is facilitated by strong dipole interactions, making it a key player in various synthetic pathways. The compound's reactivity profile is further enhanced by its compatibility with a range of solvents, allowing for diverse reaction conditions.

2,4-Dichlorobenzoyl chloride

89-75-8sc-238321
sc-238321A
5 g
100 g
$32.00
$63.00
(0)

2,4-Dichlorobenzoyl chloride is a distinctive acid halide characterized by its dichlorobenzene structure, which imparts unique electronic properties. The electron-withdrawing chlorine atoms increase the electrophilic character of the carbonyl carbon, promoting rapid acylation reactions with nucleophiles. Its planar aromatic system enhances π-stacking interactions, influencing reaction kinetics and selectivity. Additionally, the compound exhibits notable stability under various conditions, making it versatile in synthetic applications.

Phenylacetyl chloride

103-80-0sc-281128
sc-281128A
100 g
500 g
$69.00
$200.00
(0)

Phenylacetyl chloride is a notable acid halide distinguished by its aromatic ring, which contributes to its reactivity and selectivity in acylation reactions. The presence of the carbonyl group enhances its electrophilic nature, facilitating interactions with nucleophiles. Its unique steric and electronic properties allow for diverse reaction pathways, including Friedel-Crafts acylation. Furthermore, the compound's ability to form stable intermediates can influence reaction kinetics, making it a valuable reagent in organic synthesis.

Cyclopentanepropionyl chloride

104-97-2sc-223905
10 ml
$53.00
(0)

Cyclopentanepropionyl chloride is an intriguing acid halide characterized by its cyclopentane ring, which imparts unique steric effects that influence its reactivity. The carbonyl group enhances its electrophilicity, promoting rapid acylation with nucleophiles. Its distinct molecular structure allows for selective reactions, including the formation of cyclic anhydrides. Additionally, the compound's reactivity can be modulated by solvent effects, impacting the overall reaction dynamics in organic synthesis.

Isovaleryl chloride

108-12-3sc-224028
sc-224028A
25 g
100 g
$36.00
$61.00
(0)

Isovaleryl chloride is a notable acid halide distinguished by its branched structure, which introduces unique steric hindrance that affects its reactivity profile. The presence of the carbonyl group significantly increases its electrophilic character, facilitating swift acylation reactions with various nucleophiles. This compound exhibits a propensity for rearrangement reactions, leading to diverse products. Its reactivity is also influenced by temperature and solvent polarity, which can alter reaction pathways and kinetics.