Chemical inhibitors classified as Fem1al Inhibitors would be those that influence the signaling pathways associated with Fem1al function. These compounds do not interact with Fem1al directly but can modulate the activity of the pathways in which Fem1al is involved. Since Fem1al is implicated in apoptosis, compounds like Z-VAD-FMK, Staurosporine, and Nutlin-3 can impact the regulation of cell death, and thus, the activity of Fem1al. Kinase inhibitors such as U0126, SP600125, LY294002, Wortmannin, SB203580, and PD98059 can affect the MAPK, JNK, PI3K/AKT, and p38 MAPK pathways, all of which can indirectly modify Fem1al's role in cellular processes like differentiation and proliferation.
Moreover, compounds that act on cellular metabolism and stress response such as Rapamycin, Dorsomorphin, and Thapsigargin can lead to changes in the cellular environment that may affect the regulation of Fem1al. By inhibiting mTOR, AMPK, and SERCA, these chemicals can create conditions that indirectly influence Fem1al's function. It is through these multifaceted and often overlapping pathways that these chemicals can alter the activity and regulation of Fem1al within the cellular context.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
A pan-caspase inhibitor that can prevent apoptosis, indirectly affecting Fem1al's role in programmed cell death. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can influence apoptosis signaling pathways, thereby affecting Fem1al's function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
An inhibitor of MEK1/2, which can alter the MAPK/ERK pathway, indirectly influencing Fem1al's role in cell differentiation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, which can modify the JNK signaling pathway and indirectly affect Fem1al's function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can modulate the AKT signaling pathway, indirectly affecting Fem1al's activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor that can disrupt PI3K/AKT pathway signaling, influencing Fem1al's role in the process. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that can alter the p38 signaling pathway, indirectly influencing Fem1al's function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can affect the mTOR signaling pathway, which may indirectly modify Fem1al's function. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
An MDM2 antagonist that stabilizes p53, potentially influencing Fem1al's role in apoptosis. | ||||||
Dorsomorphin dihydrochloride | 1219168-18-9 | sc-361173 sc-361173A | 10 mg 50 mg | $182.00 $736.00 | 28 | |
An AMPK inhibitor, also known as Compound C, which can affect the AMPK signaling pathway and indirectly influence Fem1al. | ||||||