3010026O09Rik Activators
Chemical activators of MRN complex interacting protein play an integral role in modulating its function through various biochemical mechanisms. Adenosine triphosphate (ATP), as the primary energy currency of the cell, can activate this protein by providing the necessary energy for its conformational changes, which are crucial for its interaction with the MRN complex. Similarly, magnesium chloride can activate MRN complex interacting protein by stabilizing its structure, as magnesium ions are often necessary for the proper function of DNA repair proteins. Furthermore, nicotinamide adenine dinucleotide, known as NAD+, serves as a cofactor in redox reactions and can activate the protein by facilitating these necessary reactions within the cell, which may be required for the protein's function.
In addition to these, metal ions such as those provided by zinc sulfate and manganese(II) chloride can activate MRN complex interacting protein by inducing structural conformations necessary for its activation or by acting as cofactors to enhance its interaction capabilities with the MRN complex. Calcium chloride can also activate the protein by altering its charge state or conformation, thus promoting its functional interaction with the complex. Meanwhile, potassium chloride and sodium chloride can influence the protein's activity through ionic interactions that stabilize its structure. Reducing agents such as dithiothreitol (DTT), glutathione, and beta-mercaptoethanol play a crucial role in maintaining the protein in a reduced state, necessary for its activation and interaction with the MRN complex. Lastly, hydroxyurea can activate MRN complex interacting protein by inducing DNA damage, which in turn can enhance the recruitment and activation of the protein. Each of these chemicals assists in enabling MRN complex interacting protein to fulfill its role in the maintenance of genomic integrity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $38.00 $74.00 | 9 | |
As the primary energy currency of the cell, adenosine triphosphate (ATP) can activate MRN complex interacting protein by providing the necessary energy for its conformational changes, which are crucial for its interaction with the MRN complex. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Magnesium chloride can activate MRN complex interacting protein by stabilizing its structure and promoting its interaction with the MRN complex, as magnesium ions are often necessary for the proper function of DNA repair proteins. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Nicotinamide adenine dinucleotide (NAD+) is a cofactor in redox reactions and can activate MRN complex interacting protein by facilitating necessary redox reactions within the cell that may be required for the protein's function. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc sulfate can activate MRN complex interacting protein by binding to the protein and inducing a structural conformation necessary for its activation, as zinc is a known cofactor for many DNA-binding proteins. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Manganese(II) chloride can activate MRN complex interacting protein by acting as a cofactor, enhancing the protein's ability to interact with the MRN complex as manganese ions can influence protein-DNA interactions. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
Calcium chloride can activate MRN complex interacting protein by altering its charge state or conformation, thus promoting its functional interaction with the MRN complex, as calcium is a common signaling molecule in cells. | ||||||
Potassium Chloride | 7447-40-7 | sc-203207 sc-203207A sc-203207B sc-203207C | 500 g 2 kg 5 kg 10 kg | $25.00 $56.00 $104.00 $183.00 | 5 | |
Potassium chloride can activate MRN complex interacting protein by affecting the ionic balance and therefore the conformation of the protein, which may enhance its interaction with the MRN complex. | ||||||
Sodium Chloride | 7647-14-5 | sc-203274 sc-203274A sc-203274B sc-203274C | 500 g 2 kg 5 kg 10 kg | $18.00 $23.00 $35.00 $65.00 | 15 | |
Sodium chloride can activate MRN complex interacting protein through ionic interactions that stabilize the protein structure, potentially enhancing its ability to interact with other components of the DNA damage response. | ||||||
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $76.00 $2050.00 | 8 | |
Glutathione, in its reduced form, can activate MRN complex interacting protein by maintaining it in a reduced state that is necessary for its interaction with the MRN complex, as it may prevent oxidation that could inhibit protein function. | ||||||
β-Mercaptoethanol | 60-24-2 | sc-202966A sc-202966 | 100 ml 250 ml | $88.00 $118.00 | 10 | |
Beta-mercaptoethanol can activate MRN complex interacting protein by acting as a reducing agent, thus maintaining the protein in an active state that is capable of interacting with the MRN complex. | ||||||