1500016O10Rik Activators
RIKEN cDNA 1500016O10 gene product Activators encompass a diverse array of chemical compounds that indirectly amplify the functional activity of this protein through distinct signaling pathways. Forskolin and IBMX both raise intracellular levels of cAMP, which engages protein kinase A (PKA). PKA, in turn, can phosphorylate a plethora of substrates, potentially including those that interact with the RIKEN cDNA 1500016O10 gene product, thus enhancing its function within its biological pathway.Continuing from the previous response, the functional activity of RIKEN cDNA 1500016O10 gene product is further influenced by compounds that modulate lipid signaling and kinase activity. Sphingosine-1-phosphate (S1P), through its receptor-mediated signaling, may trigger cascades that modulate phosphorylation events, which could enhance the activity of the RIKEN cDNA 1500016O10 gene product.
The broad kinase inhibition profile of Epigallocatechin gallate (EGCG) might alter various signaling pathways, leading to an increase in the functional activity of the RIKEN cDNA 1500016O10 gene product. Additionally, PMA, as a PKC activator, and A23187, which raises intracellular calcium, could indirectly activate the RIKEN cDNA 1500016O10 gene product through phosphorylation by PKC or calcium-dependent kinases, respectively. LY294002 and U0126, by inhibiting PI3K and MEK1/2, might shift the signaling balance in a way that favors the activation of the protein, either through a reduction in competitive signaling or through the engagement of associated pathways. Collectively, these activators, via targeted effects on cellular signaling, facilitate the enhancement of functions mediated by the RIKEN cDNA 1500016O10 gene product.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Isobutylmethylxanthine (IBMX) inhibits phosphodiesterases, preventing cAMP degradation, thereby sustaining PKA activity which may enhance the functional activity of RIKEN cDNA 1500016O10 gene product through cAMP-mediated signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can modulate signaling pathways that the RIKEN cDNA 1500016O10 gene product is involved in, enhancing its activity through PKC-mediated phosphorylation events. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, potentially enhancing the activity of RIKEN cDNA 1500016O10 gene product by activating calcium-dependent protein kinases and signaling cascades. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is another calcium ionophore that raises intracellular calcium concentration, possibly enhancing the activity of RIKEN cDNA 1500016O10 gene product through calcium-mediated signaling pathways. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $106.00 $166.00 $289.00 $550.00 $819.00 | 2 | |
8-Bromoadenosine 3',5'-cyclic monophosphate (8-Br-cAMP) is a cAMP analog that activates PKA, potentially enhancing the activity of RIKEN cDNA 1500016O10 gene product by mimicking the action of cAMP on this protein's signaling pathways. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
Dibutyryl cAMP is a cell-permeable cAMP analog that activates PKA, likely enhancing the functional activity of RIKEN cDNA 1500016O10 gene product by promoting the protein's involvement in cAMP-mediated signaling processes. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram inhibits phosphodiesterase 4 (PDE4), leading to elevated cAMP levels and potentially enhancing the activity of RIKEN cDNA 1500016O10 gene product through prolonged PKA signaling. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits various protein kinases, potentially enhancing the activity of RIKEN cDNA 1500016O10 gene product by altering the phosphorylation state of proteins within its signaling pathways. | ||||||
Zaprinast (M&B 22948) | 37762-06-4 | sc-201206 sc-201206A | 25 mg 100 mg | $103.00 $245.00 | 8 | |
Zaprinast inhibits PDEs, particularly PDE5, which may enhance the activity of RIKEN cDNA 1500016O10 gene product by increasing cAMP and/or cGMP levels, affecting PKA and PKG signaling pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that can enhance the activity of RIKEN cDNA 1500016O10 gene product by modulating the phosphorylation state of proteins within its signaling network, potentially leading to enhanced protein function. | ||||||