TCP-1 θ Antibody (E-1): sc-377453
- TCP-1 θ Antibody (E-1) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-29 at the N-terminus of TCP-1 θ of human origin
- recommended for detection of TCP-1 θ of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TCP-1 θ Antibody (E-1) for WB and IHC(P) applications. These reagents are now offered in bundles with TCP-1 θ Antibody (E-1) (see ordering information below).
TCP-1 θ Antibody (E-1) is a mouse monoclonal IgG1 antibody that detects TCP-1 θ in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). TCP-1 θ is a crucial subunit of the chaperonin containing TCP-1 (CCT) complex, which is essential for the proper folding of cytosolic proteins, particularly actins and tubulins. The CCT complex is composed of eight distinct subunits, each encoded by different genes, and TCP-1 θ plays a significant role in ensuring the correct assembly and functionality of these proteins, which are vital for numerous cellular processes including cytoskeletal organization and intracellular transport. The proper folding of actins and tubulins is critical, as misfolded proteins can lead to cellular dysfunction and contribute to various diseases. TCP-1 θ has been shown to interact with other subunits of the CCT complex, enhancing its chaperoning capabilities, and TCP-1 θ expression is tightly regulated during development and in response to cellular stress. Anti-TCP-1 θ antibody (E-1) is an invaluable tool for researchers studying protein folding mechanisms and the role of chaperonins in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TCP-1 θ Antibody (E-1) | sc-377453 | 200 µg/ml | $322.00 | |||
TCP-1 θ Antibody (E-1): m-IgG Fc BP-HRP Bundle | sc-540720 | 200 µg Ab; 10 µg BP | $361.00 | |||
TCP-1 θ Antibody (E-1): m-IgG1 BP-HRP Bundle | sc-542322 | 200 µg Ab; 20 µg BP | $361.00 | |||
TCP-1 θ (E-1) Neutralizing Peptide | sc-377453 P | 100 µg/0.5 ml | $69.00 |