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SNAT2 抗体 (C-6): sc-514037

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说明书
  • SNAT2抗体(C-6)是小鼠单克隆IgG2a κ, 在5篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列1-60位于human物种的SNAT2的N-terminus
  • 抗-SNAT2 抗体 (C-6) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 SNAT2
  • 抗SNAT2抗体(C-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取SNAT2 (C-6): sc-514037免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRP是SNAT2 Antibody (C-6) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与SNAT2 Antibody (C-6) 打包提供(请参阅下面的订购信息)。

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関連項目

SNAT2抗体(C-6)是一种IgG2a κ小鼠单克隆SNAT2抗体,可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的SNAT2。SNAT2抗体(C-6)既可以是非偶联的抗SNAT2抗体形式,也可以是多种偶联形式的抗SNAT2抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。SLC38基因家族的钠偶联中性氨基酸转运体(SNAT)包括系统A亚型SNAT1、SNAT2和SNAT4以及系统N亚型SNAT3和SNAT5。SLC38转运体对于营养物质的摄取、能量产生、代谢、解毒以及神经递质的循环至关重要。SNAT2也称为ATA2、PRO1068和SAT2,由人类基因SLC38A2编码。SNAT2在神经系统中的功能作用尚不清楚。蛋白质表达在听觉系统的脊髓和脑干核中显著富集。系统A转运蛋白也存在于胎盘组织中。这些SNAT蛋白可能在胎儿发育中发挥重要作用,而转运系统的抑制与胎儿生长迟缓有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SNAT2 抗体 (C-6) 参考文献:

  1. 中性氨基酸转运体 SNAT2 在细胞容量调节中的作用  |  Franchi-Gazzola, R., et al. 2006. Acta Physiol (Oxf). 187: 273-83. PMID: 16734764
  2. 在新皮层神经元中,SNAT2 氨基酸转运体受 SLC6 γ-氨基丁酸转运体亚家族的氨基酸调控,在为谷氨酸能传导提供谷氨酰胺方面可能不起作用。  |  Grewal, S., et al. 2009. J Biol Chem. 284: 11224-36. PMID: 19240036
  3. SNAT2 受体通过 mTOR 发出信号:在细胞生长和增殖中发挥作用?  |  Pinilla, J., et al. 2011. Front Biosci (Elite Ed). 3: 1289-99. PMID: 21622135
  4. 人类生长受限胎盘中 SNAT2 的表达与调控  |  Mandò, C., et al. 2013. Pediatr Res. 74: 104-10. PMID: 23728383
  5. 大鼠钠偶联中性氨基酸转运体 2(SNAT2)的膜拓扑结构。  |  Ge, Y., et al. 2018. Biochim Biophys Acta Biomembr. 1860: 1460-1469. PMID: 29678469
  6. 缺氧诱导的SNAT2/SLC38A2调控转换产生乳腺癌的内分泌抗药性  |  Morotti, M., et al. 2019. Proc Natl Acad Sci U S A. 116: 12452-12461. PMID: 31152137
  7. ChREBP 通过与 SMRT 相互作用下调 SNAT2 氨基酸转运体的表达,以应对高碳水化合物饮食。  |  Velázquez-Villegas, L., et al. 2021. Am J Physiol Endocrinol Metab. 320: E102-E112. PMID: 33225719
  8. SNAT2 在人前列腺 PC-3 细胞中负责高渗透诱导的肌氨酸和甘氨酸摄取。  |  Nielsen, CU., et al. 2022. Pflugers Arch. 474: 1249-1262. PMID: 36175560
  9. 潜在非氨基酸 SNAT2 抑制剂的研究。  |  Jakobsen, S., et al. 2023. Front Pharmacol. 14: 1302445. PMID: 38239202
  10. SNAT2 在山羊乳腺上皮细胞增殖过程中介导的雌激素和孕酮调节作用  |  Jiang, T., et al. 2024. Amino Acids. 56: 17. PMID: 38393495

订购信息

产品名称产品编号规格价格数量收藏夹

SNAT2 抗体 (C-6)

sc-514037
200 µg/ml
$316.00

SNAT2 (C-6): m-IgG Fc BP-HRP 套装

sc-526343
200 µg Ab; 10 µg BP
$354.00

SNAT2 (C-6): m-IgG2a BP-HRP 套装

sc-546595
200 µg Ab; 10 µg BP
$354.00

SNAT2 抗体 (C-6) AC

sc-514037 AC
500 µg/ml, 25% agarose
$416.00

SNAT2 抗体 (C-6) HRP

sc-514037 HRP
200 µg/ml
$316.00

SNAT2 抗体 (C-6) FITC

sc-514037 FITC
200 µg/ml
$330.00

SNAT2 抗体 (C-6) PE

sc-514037 PE
200 µg/ml
$343.00

SNAT2 抗体 (C-6) Alexa Fluor® 488

sc-514037 AF488
200 µg/ml
$357.00

SNAT2 抗体 (C-6) Alexa Fluor® 546

sc-514037 AF546
200 µg/ml
$357.00

SNAT2 抗体 (C-6) Alexa Fluor® 594

sc-514037 AF594
200 µg/ml
$357.00

SNAT2 抗体 (C-6) Alexa Fluor® 647

sc-514037 AF647
200 µg/ml
$357.00

SNAT2 抗体 (C-6) Alexa Fluor® 680

sc-514037 AF680
200 µg/ml
$357.00

SNAT2 抗体 (C-6) Alexa Fluor® 790

sc-514037 AF790
200 µg/ml
$357.00

we are using the primary mouse antibody (1:300) and the secondary antibody produced in goat (1:5000). but it is not showing any result. what will be the explanation?

Asked by: addy
Thank you for your question. There are many different aspects that can affect the outcome of your experiment. Please contact our technical service directly for troubleshooting advice.
Answered by: Technical Support Europe
Date published: 2020-10-23

Hi, How can I get the FREE 10 µg sample of SNAT2 (C-6): sc-514037?

Asked by: Shin_Hayashi
Please contact our Technical Service Department for more information on how to receive a free 10 ug sample of this monoclonal antibody.
Answered by: Technical Support
Date published: 2018-12-03

What is the recommended fixation method for immunofluorescence staining with SNAT2 (C-6): sc-514037 monoclonal antibody?

Asked by: AbPolly
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from clean bandno background staining is seen with PVDF membranes,I can see clean and specific band at 60kda, use Hela cell.
Date published: 2017-07-01
Rated 5 out of 5 by from good result for WB and IFVery clear, highly specific IF staining; also strong band for WB.
Date published: 2017-06-03
Rated 5 out of 5 by from Produced beautiful immunofluorescence membraneProduced beautiful immunofluorescence membrane and cytoplasmic vesicles staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-05-01
Rated 5 out of 5 by from Nice Western Blot data of SNAT2 expression in nonNice Western Blot data of SNAT2 expression in non-transfected and human SNAT2 transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-12-04
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SNAT2 抗体 (C-6) is rated 5.0 out of 5 by 4.
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