SMUG1 Antibody (H-11): sc-271580
- SMUG1 Antibody (H-11) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 46-94 mapping near the N-terminus of SMUG1 of human origin
- recommended for detection of SMUG1 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SMUG1 Antibody (H-11). This work is in progress.
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SEE ALSO...
SMUG1 Antibody (H-11) is a mouse monoclonal IgG2b antibody that detects SMUG1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SMUG1, or single-strand selective monofunctional uracil DNA glycosylase, plays a crucial role in the base excision repair (BER) pathway by specifically removing uracil from DNA, thereby preventing mutations that could lead to genomic instability and various diseases, including cancer. SMUG1 maintains DNA integrity by recognizing and excising uracil, which can arise from cytosine deamination or be incorporated during DNA replication. SMUG1 is predominantly located in the nucleus, where SMUG1 interacts with chromatin, ensuring that damaged DNA is efficiently repaired. The human SMUG1 gene is located on chromosome 12q13.13, and SMUG1 expression is vital for cellular health, as deficiencies in this repair mechanism can lead to an accumulation of DNA damage. anti-SMUG1 antibody (H-11) is an essential tool for researchers studying DNA repair mechanisms and their implications in disease, providing reliable detection and characterization of this important protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SMUG1 Antibody (H-11) | sc-271580 | 200 µg/ml | $322.00 |